Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation
- Nitrate and nitrosative chemistry within Barrett's oesophagus during acid reflux. Suzuki, H.; Iijima, K.; Scobie, G.; Fyfe, V.; McColl, K. E. L. // Gut;Nov2005, Vol. 54 Issue 11, p1527
Background and aims: When saliva, with its high nitrite content derived from the enterosalivary recirculation of dietary nitrate, meets acidic gastric juice, the nitrite is converted to nitrous acid, nitrosative species, and nitric oxide. In healthy volunteers this potentially mutagenic...
- Effects of Ascorbic Acid Treatment to Grapevine Rootstock-1616C and Vitis vinifera L. cvs. Razaki. Yildirim, Özlem // Asian Journal of Biochemistry;2007, Vol. 2 Issue 6, p395
The glutathione contents, ascorbic acid, nitric oxide, lipid peroxide levels and the activities of free radical scavenging enzymes were examined using five different concentrations of ascorbic acid treated RazakÄ± cultivar and 1616C rootstock. Reduced glutathione was increased with ascorbic...
- EPC-K1 PROTECTS NEURONAL CELLS FROM PEROXYNITRITE-MEDIATED OXIDATIVE DAMAGE. Wei, Taotao; Xin, Wenjuan; Hou, Jingwu; Chen, Chang; Mori, Akitane // Research on Chemical Intermediates;2000, Vol. 26 Issue 7/8, p667
Presents a study which examined the protective effects of EPC-K1 on neuronal cell damage mediated by peroxynitrite using primary culture of rat cerebellar granule cells as a model. Overview of nitric oxide; Experimental procedure; Results and discussion.
- Another Reason to Eat Your Vegetables--Nitric Oxide. // Consumers' Research Magazine;Feb2000, Vol. 83 Issue 2, p41
Reports on the health benefits of nitric oxide (NO). How the nitrates found in the food are converted into nitrites; Examples of studies on nitric oxide.
- Nitrite content and antioxidant enzyme levels in the blood of schizophrenia patients. Srivastava, Nupur; Barthwal, Manoj K.; Dalal, Pranob K.; Agarwal, Anil K.; Nag, Devika; Srimal, Rikhab C.; Seth, Prahlad K.; Dikshit, Madhu // Psychopharmacology;2001, Vol. 158 Issue 2, p140
Rationale: Recent studies have suggested augmentation in the inflammatory response as well as involvement of nitric oxide (NO) in mood disorders. Polymorphonuclear leukocytes (PMN), NO and free radicals have been associated with inflammatory response; however, the status of NO in the PMN has not...
- Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress Clapp, Brian R.; Hingorani, Aroon D.; Kharbanda, Rajesh K.; Mohamed-Ali, Vidya; Stephens, Jeffrey W.; Vallance, Patrick; MacAllister, Raymond J. // Cardiovascular Research;Oct2004, Vol. 64 Issue 1, p172
Our aim was to investigate mechanisms of inflammation-induced endothelial dysfunction in humans.Endothelial function in twenty-one healthy human volunteers was measured using forearm venous plethysmography before and 8 h after administration of typhoid vaccination to generate an inflammatory...
- VITAMIN C FOR BOOSTING NO. // Muscle & Performance;Mar2012, Vol. 4 Issue 3, p12
The article recommends the intake of vitamin C together with arginine and other pre-workout supplements to boost immunity and to combat free radicals which break down nitric oxide.
- Nitrosative Stress as a Mediator of Apoptosis: Implications for Cancer Therapy. Hirst, David G.; Robson, Tracy // Current Pharmaceutical Design;1/1/2010, Vol. 16 Issue 1, p45
Nitric oxide (NOÂ·) is now recognised as one of the most important molecules influencing the development, progression and treatment of cancer. A key component of its action is as a negative and positive regulator of apoptosis. Broadly, constitutive levels of NOÂ· (nM), are capable of...
- Effect of asymmetric dimethylarginine on osteoblastic differentiation. Xiao, Z. Sheng; Quarles, L. Darryl; Chen, Q. Quan; Yu, Y. Hui; Qu, X. Ping; Jiang, C. Hong; Deng, H. Wu; Li, Y. Jian; Zhou, H. Hao; Xiao, Z S; Quarles, L D; Chen, Q Q; Yu, Y H; Qu, X P; Jiang, C H; Deng, H W; Li, Y J; Zhou, H H // Kidney International;Nov2001, Vol. 60 Issue 5, p1699
Background:Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS) that accumulates in renal insufficiency and may be a uremic toxin. To determine whether ADMA inhibits bone metabolism, we investigated the in vitro effect of ADMA on osteoblastic...