TITLE

Urine Drug Screening: Practical Guide for Clinicians

AUTHOR(S)
Moeller, Karen E.; Lee, Kelly C.; Kissack, Julie C.
PUB. DATE
January 2008
SOURCE
Mayo Clinic Proceedings;Jan2008, Vol. 83 Issue 1, p66
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common method for analysis because of ease of sampling. The simplicity of use and access to rapid results have increased demand for and use of immunoassays; however, these assays are not perfect. False-positive results of immunoassays can lead to serious medical or social consequences if results are not confirmed by secondary analysis, such as gas chromatography-mass spectrometry. The Department of Health and Human Services' guidelines for the workplace require testing for the following 5 substances: amphetamines, cannabinoids, cocaine, opiates, and phencyclidine. This article discusses potential false-positive results and false-negative results that occur with immunoassays of these substances and with alcohol, benzodiazepines, and tricyclic antidepressants. Other pitfalls, such as adulteration, substitution, and dilution of urine samples, are discussed. Pragmatic concepts summarized in this article should minimize the potential risks of misinterpreting urine drug screens.
ACCESSION #
28095607

 

Related Articles

  • ACP treatment guideline for antidepressants. Elliott, William T. // Travel Medicine Advisor;Jan2008 Supplement, p2 

    The article discusses a guideline issued by the American College of Physicians on the use of "second-generation antidepressants." The group recommends that antidepressants should be chosen on the basis of negative effect, cost and patient option. Further recommendations by the group include that...

  • Review: short-term benefit of escitalopram versus citalopram for depression uncertain, but big difference in French health insurance costs. Cipriani, Andrea; Barbui, Corrado // Evidence Based Mental Health;May2013, Vol. 16 Issue 2, p51 

    The article discusses the uncertainty associated with the efficacy of citalopram compared with escitalopram in people with depression. It includes a study wherein randomized controlled trials (RCTS) were carried out on patients with major depression. It concludes that the short-term efficacy and...

  • Screening for inherited metabolic disease in newborn infants using tandem mass spectrometry. Leonard, James V; Dezateux, Carol // BMJ: British Medical Journal (International Edition);1/5/2002, Vol. 324 Issue 7328, p4 

    Editorial. Discusses the use of tandem mass spectrometry to screen newborns for medium chain acyl CoA dehydrogenase deficiency, an inherited metabolic disease. How the disease usually presents during infancy and early childhood causing death or irreversible neurological damage; Lack of uniform...

  • THE EUROPEAN COURT OF JUSTICE AND WORKING TIME IN THE HEALTH CARE SECTOR: RELEVANCE TO THE CZECH REPUBLIC. Den Exter, André // Medicine & Law;2005, Vol. 24 Issue 2, p337 

    In a recent court ruling, the European Court of Justice concluded that a Member State violated the European Directive on working time. The issue concerned the meaning of working time as defined by the Directive. It appeared that the time an employee is present and available at the workplace,...

  • Factors associated with antidepressant medication adherence and adherenceenhancement programmes: a systematic literature review. Servellen, Gwen van; Heise, Barbara A.; Ellis, Robin // Mental Health in Family Medicine;2011, Vol. 8 Issue 4, p255 

    Medication adherence is critical to the efficacy of available treatment for depression in primary care settings. This review identifies factors associated with adherence and what is known about the effectiveness of adherence-enhancement programmes. A comprehensive systematic review of English...

  • Role of SSRIs in pediatric depression management. Cao, Christina Ngoc; Annis, Laura G. // Drug Topics;11/8/2004, Vol. 148 Issue 21, p60 

    This article examines the role of a group of antidepressants called selective serotonin reuptake inhibitors (SSRIs) in pediatric depression management. It aims to help pharmacists understand the prevalence of pediatric depression, the treatment options, and the U.S. Food and Drug Administration...

  • Treatment of Depression in Patients with Dementia.  // Critical Care Alert;Oct2011 Clinical Briefs Supplement, p19 

    No abstract available.

  • Treatment of Depression in Patients with Dementia.  // Clinical Cardiology Alert;Oct2011 Clinical Briefs, p19 

    The article reports a study by S. Banerjee and colleagues, which concluded that sertraline and mirtazapine did not provide improvements in the Cornell Scale for Depression in Dementia (CSDD) scores compared to placebo, thus suggesting a reconsideration of preferred treatment options for dementia.

  • Treatment of Depression in Patients with Dementia. Kuritzky, Louis // Clinical Oncology Alert;Oct2011 Supplement, p19 

    No abstract available.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics