Blue genes

December 2007
Marketing Health Services;Winter2007, Vol. 27 Issue 4, p8
Academic Journal
The article reports that two genetic markers are linked with suicidal thoughts in patients taking the antidepressant citalopram or Celexa, according to research from the National Institute of Mental Health. Forest Labs, which manufactures Celexa, reports that 8 million people in the U.S. and 30 million worldwide, have been prescribed the drug. Scientists screened genetic material from adults with major depression who were taking Celexa. The author reveals that variants of the genes GRIK2 and GRIA3, which regulate how the brain processes glutamate, an amino acid that helps mediate communication between brain neurons, increased the chances that those adults would contemplate suicide.


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