TITLE

Clinical and mycological profile of cryptococcosis in a tertiary care hospital

AUTHOR(S)
Capoor, M. R.; Nair, D.; Deb, M.; Gupta, B.; Aggarwal, P.
PUB. DATE
October 2007
SOURCE
Indian Journal of Medical Microbiology;Oct2007, Vol. 25 Issue 4, p401
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
This study examined the extent of cryptococcosis in clinically diagnosed cases of meningitis in HIV-1 seropositive and apparently immunocompetent patients. One hundred and forty-six samples, obtained from 126 chronic meningitis patients comprised of cerebrospinal fluid (CSF), blood, sputum and urine. The samples were processed by standard microbiological procedures. Cryptococcal isolates were identified by microscopy, cultural characteristics, melanin production on niger seed agar and hydrolysis of urea. The isolates were further speciated on cannavanine glycine bromothymol blue (CGB) media. Cryptococcal antigen detection of CSF samples was performed by latex agglutination test (LAT). Minimum inhibitory concentration (MIC) of amphotericin B for the isolates was also tested. Cryptococcosis was diagnosed in 13 patients (eight HIV-1 seropositive and five apparently immunocompetent). Cryptococcus neoformans var. neoformans was the predominant isolate. Cryptococcal antigen was detected in all, whereas microscopy could detect yeast cells in nine patients. The isolates were sensitive to amphotericin B. CD4 cell counts ranged from 8 to 96/cu mm. The study concludes that all CSF samples with clinical diagnosis of subacute and chronic meningitis should be subjected to tests for detection of Cryptococcus in clinical laboratory irrespective of the immune status.
ACCESSION #
28056847

 

Related Articles

  • Clinico-mycological profile of cryptococcosis in a tertiary care.  // New Indian Journal of Surgery;Apr2011, Vol. 2 Issue 2, p104 

    An abstract of the article "Clinico-mycological profile of cryptococcosis in a tertiary care," by P. Varshney, M. R. Capoor, B. K. Tripathi, C. Raghvan, M. Deb, P. Aggarwal, and D. C. Jain is presented.

  • Major Role for Amphotericin B-Flucytosine Combination in Severe Cryptococcosis. Dromer, Fran├žoise; Bernede-Bauduin, Claire; Guillemot, Didier; Lortholary, Olivier // PLoS ONE;2008, Vol. 3 Issue 8, p1 

    Background: The Infectious Diseases Society of America published in 2000 practical guidelines for the management of cryptococcosis. However, treatment strategies have not been fully validated in the various clinical settings due to exclusion criteria during therapeutic trials. We assessed here...

  • PITYRIASIS VERSICOLOR: A CLINICOMYCOLOGICAL AND EPIDEMIOLOGICAL STUDY FROM A TERTIARY CARE HOSPITAL. Ghosh, Sudip Kumar; Dey, Sunil Kumar; Saha, Indranil; Barbhuiya, Jayasree Nath; Ghosh, Arghyaprasun; Roy, Aloke Kumar // Indian Journal of Dermatology;Oct-Dec2008, Vol. 53 Issue 4, p182 

    Background: Pityriasis versicolor is a mild, chronic, usually asymptomatic superficial fungal infection of the stratum corneum, caused by Malassezia yeasts. The purpose of the present study is to assess the clinical profile of a group of patients with pityriasis versicolor and to find out the...

  • Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal. Khadka, Sundar; Sherchand, Jeevan Bahadur; Pokharel, Dinesh Binod; Pokhrel, Bharat Mani; Mishra, Shyam Kumar; Dhital, Subhash; Rijal, Basista // Dermatology Research & Practice;11/24/2016, p1 

    Background. Superficial mycosis is a common fungal infection worldwide, mainly caused by dermatophytes. However, the prevalence of species varies geographically. In addition, fungal treatment is best guided according to species isolated. This study was carried out to determine the clinical as...

  • PULMONARY CRYPTOCOCCOSIS: TREATMENT WITH AMPHOTERICIN B. Durant, John R.; Epifano, Leonard D.; Eyer, Simon W. // Annals of Internal Medicine;Sep60, Vol. 53 Issue 3, p534 

    Presents clinical cases of pulmonary cryptococcosis. Clinical profile of the patients; Results of the physical examination; Treatment management.

  • Clinical profile of patients with traumatic cervical spine injury in the emergency department of a tertiary care hospital. Wills, Shiju Jesudas; Pandian, Gautham Raja; Bhanu, Thomas Kurien; Kumar, Kirthi Sathya; Murugan, Yuvaraja; Prabhakar Abhilash, Kundavaram Paul // Journal of Emergencies, Trauma & Shock;Jan-Mar2016, Vol. 9 Issue 1, p43 

    A letter to the editor is presented which discusses the clinical profile of patients with traumatic cervical spine injury in a tertiary hospital.

  • Overview of Opportunistic Fungal Infections in India. Chakrabarti, Arunaloke; Chatterjee, Shiv Sekhar; Shivaprakash, M. R. // Japanese Journal of Medical Mycology;Sep2008, Vol. 49 Issue 3, p165 

    In recent years fungi have been flourishing in immunocompromised patients of tertiary care centers. The data on the burden of opportunistic mycoses in India is not clear though the climate in this country is well suited for a wide variety of fungal infections. There are very few good diagnostic...

  • Profile Of Patients With Lung Cancer Attending A Tertiary Care Hospital. Fazal, Abdul Rahim; Varughese, Sunny; Suhail, N.; Mohan, Mithun C. // Nepal Journal of Epidemiology;2014, Vol. 4 Issue 2, p11 

    An abstract of the article "Profile of Patients With Lung Cancer Attending a Tertiary Care Hospital," by Abdul Rahim Fazal and colleagues is presented.

  • Clinical Profile Of Patients With Leptospirosis In A Tertiary Care Centre In North Kerala. Mohan, Mithun C.; Sudeep, K.; Karunakaran, Usha; Abdullah, Mariya; Shibu, Joseph; Nair, Haritha; Mukundan, Mukesh // Nepal Journal of Epidemiology;2014, Vol. 4 Issue 2, p7 

    An abstract of the article "Clinical Profile Of Patients With Leptospirosis In A Tertiary Care Centre In North Kerala," by Mithun C. Mohan and colleagues is presented.

  • Cryptococcal Meningitis in a Tertiary Care Hospital. Juhi, Taneja; BibhaBati, Mishra; Aradhana, Bhargava; Poonam, Lcomba; Vinita, Dogra; Archana, Thakur // Japanese Journal of Medical Mycology;Jun2009, Vol. 50 Issue 2, p95 

    Seven cases of cryptococcus meningitis in a tertiary care hospital from 2004-2007 were reviewed. 85.7% of the patients had headache as their predominant clinical feature. The spectrum of CT/MR findings ranged from no abnormality, basal ganglion lesion, to intracerebral and intraventricular...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics