Rosiglitazone increased heart failure but did not differ from metformin plus sulfonylurea for other CV outcomes at interim analysis

November 2007
ACP Journal Club;Nov/Dec2007, Vol. 147 Issue 3, p67
Academic Journal
The article focuses on a clinical study investigating the effectiveness level of rosiglitazone (RGZ) over metformin (MFN) and sulfonylurea (SFU), as an add-on therapy of cardiovascular (CV) diseases. It discusses the procedure followed along with the randomized controlled trial (RCT), carried out during the study. It mentions that the study revealed an increase in the risk of heart failure due to RGZ, but no difference was found between RGZ and MFN plus CFU, for other CV outcomes.


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