Warfarin reduced major stroke more than aspirin in elderly patients with atrial fibrillation in primary care
- ASA or low-molecular-weight heparin in the initial management of acute ischemic stroke complicating atrial fibrillation? Farquhar, Donald // CMAJ: Canadian Medical Association Journal;2/06/2001, Vol. 164 Issue 3, p396
Reports on a study to determine if low-molecular-weight heparin (LMWH) is superior to aspirin in preventing early recurrent ischemic stroke in patients with atrial fibrillation. Background; Design; Results; Conclusion that there is no evidence that anticoagulation with LMWH is superior to...
- Suboptimal warfarin use in AF significant economic burden. // PharmacoEconomics & Outcomes News;5/25/2013, Issue 679, p6
The article reports that a retrospective, observational study conducted in the U.S. from January 2003-December 2007 has concluded that underuse of warfarin and non-adherence among patients with atrial fibrillation (AF) led to an increase in healthcare resources use and total medical care cost.
- COMMENTARY: Warfarin reduced major stroke more than aspirin in elderly patients with atrial fibrillation in primary care. Jaffer, Amir K. // ACP Journal Club;Nov/Dec2007, Vol. 147 Issue 3, p59
The author reflects on the findings of a study, that focused on the effectiveness of warfarin, over aspirin in elderly primary care patients with atrial fibrillation (AF). He states that even though stroke risk in AF, warfarin is underutilized to cure elderly patients suffering from AF. He...
- How Should Results from Completed Studies Influence Ongoing Clinical Trials? Laupacis, Andreas; Connolly, Stuart J.; Gent, Michael; Roberts, Robin S.; Cairns, John; Joyner, Campbell // Annals of Internal Medicine;11/15/91, Vol. 115 Issue 10, p818
Presents a study which evaluated the efficacy of warfarin or aspirin or both in decreasing the risk of embolic events in patients with nonrheumatic atrial fibrillation. Description of atrial fibrillation and the clinical studies; Influence of completed studies on ongoing clinical trials.
- Aspirin may increase bleeding risk in atrial fibrillation patients on oral anticoagulants. // Hem/Onc Today;9/25/2013, Vol. 14 Issue 18, p10
The article focuses on researcher B.A. Steinberg's analysis of data from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry which indicated that concomitant aspirin therapy may increase bleeding risk in patients with atrial fibrillation (AF).
- Clopidogrel + aspirin in atrial fibrillation. // Neurology Alert;Aug2009 Clinical Briefs in, Vol. 14 Issue 8, p15
The article discusses the effect of clopidogrel (CPG) when combined with aspirin (ASA) in the treatment of patients with atrial fibrillation (FIB). It references a study by The ACTIVE Investigators, published in the 2009 issue of "N Engl J Med." Some FIB patients with indications for coumadin...
- Clopidogrel + aspirin in atrial fibrillation. Kuritzky, Louis // Clinical Cardiology Alert;Aug2009 Clinical Briefs in, Vol. 14 Issue 8, p15
The article discusses research on the clinical use of clopidogrel and aspirin in atrial fibrillation. It references the study "The ACTIVE Investigators. Effect of Clopidogrel Added to Aspirin in Patients With Atrial Fibrillation," published in the 2009 issue of the "New England Journal of...
- Warfarin vs Clopidogrel Plus Aspirin for Atrial Fibrillation. DiMarco, John P. // Clinical Cardiology Alert;Jan2008, Vol. 27 Issue 1, p4
The atrial fibrillation clopidogrel trial with Irbesartan for Prevention of Vascular Events (ACTIVE W) is a noninferiority trial comparing anticoagulation with warfarin to therapy with aspirin plus clopidogrel for stroke prevention in patients with atrial fibrillation. ACTIVE W enrolled 6706...
- Warfarin vs Aspirin for Atrial Fibrillation in the Elderly. Crawford, Michael H. // Clinical Cardiology Alert;Oct2007, Vol. 26 Issue 10, p73
OVER HALF OF PATIENTS WITH ATRIAL FIBRILLATION ARE OVER age 75 years, yet there is concern about the risk of serious hemorrhage in these patients on warfarin. Thus, the results of the Birmingham Atrial Fibrillation Treatment of the Aged (BAFTA) study are of interest. BAFTA was a prospective...