SERS: a versatile tool in chemical and biochemical diagnostics

Hering, Katharina; Cialla, Dana; Ackermann, Katrin; Dörfer, Thomas; Möller, Robert; Schneidewind, Henrik; Mattheis, Roland; Fritzsche, Wolfgang; Rösch, Petra; Popp, Jürgen
January 2008
Analytical & Bioanalytical Chemistry;Jan2008, Vol. 390 Issue 1, p113
Academic Journal
Raman spectroscopy is a valuable tool in various research fields. The technique yields structural information from all kind of samples often without the need for extensive sample preparation. Since the Raman signals are inherently weak and therefore do not allow one to investigate substances in low concentrations, one possible approach is surface-enhanced (resonance) Raman spectroscopy. Here, rough coin metal surfaces enhance the Raman signal by a factor of 104–1015, depending on the applied method. In this review we discuss recent developments in SERS spectroscopy and their impact on different research fields.


Related Articles

  • The Impact of Spatial Sampling Density in Raman Imaging. Lee, Eunah; Adar, Fran; Whitely, Andrew // Spectroscopy;Sep2006 Supplement, Vol. 21, p16 

    The article offers information about the study on the possibility that Raman mapping can combine the sensitivity and selectivity of vibrational spectroscopy with the high spatial resolution of a confocal microscope. Furthermore, the study aims at selecting the optimum spatial sampling density...

  • Thermodynamic and Raman Spectroscopic Studies of Ar Hydrate System. Sugahara, Keisuke; Kaneko, Ryuji; Sasatani, Arata; Sugahara, Takeshi; Ohgaki, Kazunari // Open Thermodynamics Journal;2008, Vol. 2, p95 

    The three-phase coexisting curve of Ar hydrate + water + gas has been investigated in a pressure range up to 485 MPa and a temperature range of (279.57 to 305.32) K. The Raman spectrum of intermolecular O-O stretching vibration mode has been measured for Ar hydrate crystal along the stability...

  • In situ high pressure-temperature Raman spectroscopy technique with laser-heated diamond anvil cells. Jung-Fu Lin; Santoro, Mario; Struzhkin, Viktor V.; Ho-kwang Mao; Hemley, Russell J. // Review of Scientific Instruments;Oct2004 Part I & II, Vol. 75 Issue 10, p3302 

    We describe an in situ high pressure-temperature Raman technique for studying materials in laser-heated diamond anvil cells using a Nd:YLF laser (1053 nm) as the heating source and an ion laser as the Raman exciting source. Here we introduce the method of laser heating transparent samples using...

  • Micro-Raman Mapping of 3C-SiC Thin Films Grown by Solid–Gas Phase Epitaxy on Si (111). Perova, T.; Wasyluk, J.; Kukushkin, S.; Osipov, A.; Feoktistov, N.; Grudinkin, S. // Nanoscale Research Letters;Sep2010, Vol. 5 Issue 9, p1507 

    A series of 3C-SiC films have been grown by a novel method of solid–gas phase epitaxy and studied by Raman scattering and scanning electron microscopy (SEM). It is shown that during the epitaxial growth in an atmosphere of CO, 3C-SiC films of high crystalline quality, with a thickness of...

  • Polarization dependence of vibrational coupling signals in femtosecond stimulated Raman spectroscopy. Frontiera, Renee R.; Mathies, Richard A. // Journal of Chemical Physics;9/28/2007, Vol. 127 Issue 12, p124501 

    The polarization dependence of vibrational coupling signals seen in femtosecond stimulated Raman spectroscopy (FSRS) is investigated. Changing the polarization of a pulse used to impulsively excite coherent low frequency chlorine bending motion in CDCl3 has a dramatic effect on the line shape of...

  • The Effect of Hydration of Ions of Inorganic Salts on the Shape of the Raman Stretching Band of Water. Burikov, S.A.; Dolenko, T.A.; Velikotny&icaron;, P.A.; Sugonyaev, A.V.; Fadeev, V.V. // Optics & Spectroscopy;Feb2005, Vol. 98 Issue 2, p235 

    The shape of the Raman stretching band of water molecules in aqueous solutions of electrolytes KBr, KCl, KI, NaCl, and NaI is studied. It is confirmed that the characteristics of the stretching band strongly depend on the concentration and type of salt. The behavior of different parameters of...

  • Highly efficient tip-enhanced Raman spectroscopy and microscopy of strained silicon. Tarun, Alvarado; Hayazawa, Norihiko; Motohashi, Masashi; Kawata, Satoshi // Review of Scientific Instruments;Jan2008, Vol. 79 Issue 1, p013706 

    We present a versatile tip-enhanced Raman spectroscopy (TERS) system that permits efficient illumination and detection of optical properties in the visible range to obtain high signal-to-noise Raman signals from surfaces and interfaces of materials using an edge filter. The cutoff wavelength of...

  • Ru doping induced quantum paraelectricity in ferroelectric Sr0.9Ba0.1TiO3. Wei, T.; Guo, Y. J.; Wang, P. W.; Yu, D. P.; Wang, K. F.; Lu, C. L.; Liu, J.-M. // Applied Physics Letters;4/28/2008, Vol. 92 Issue 17, p172912 

    We investigate the effect of Ru doping on the dielectric and ferroelectric behaviors of polycrystalline Sr0.9Ba0.1TiO3. It is observed that the Ru doping significantly suppresses the ferroelectric mode, as evidenced by the Raman spectroscopy at various temperatures. The enhanced quantum...

  • A preservation study of carbon nanotubes in alumina-based nanocomposites via Raman spectroscopy and nuclear magnetic resonance. Thomson, K. E.; Jiang, Dongtao; Ritchie, R. O.; Mukherjee, A. K. // Applied Physics A: Materials Science & Processing;Nov2007, Vol. 89 Issue 3, p651 

    Raman spectroscopy was used to study the preservation of the carbon nanotube structure in nanotube-reinforced alumina nanocomposites consolidated via spark plasma sintering (SPS). A series of Raman spectroscopy experiments was used to identify the thermal breakdown temperature of single-walled...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics