Chemometric experimental design based optimization techniques in capillary electrophoresis: a critical review of modern applications

Hanrahan, Grady; Montes, Ruthy; Gomez, Frank A.
January 2008
Analytical & Bioanalytical Chemistry;Jan2008, Vol. 390 Issue 1, p169
Academic Journal
A critical review of recent developments in the use of chemometric experimental design based optimization techniques in capillary electrophoresis applications is presented. Current advances have led to enhanced separation capabilities of a wide range of analytes in such areas as biological, environmental, food technology, pharmaceutical, and medical analysis. Significant developments in design, detection methodology and applications from the last 5 years (2002–2007) are reported. Furthermore, future perspectives in the use of chemometric methodology in capillary electrophoresis are considered.


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