Yaşa Bağlı Maküla Dejeneresansı Gelişiminde Serum Kan Lipid Profilinin Rolü

Yaylali, Sevil Ari; Akçakaya, Aylin Ardagil; Acar, Hüseyin; Sönmez, Ayşe; Aydin, Nihat; Erbil, Hasan H.
September 2007
Retina-Vitreus/Journal of Retina-Vitreous;Sep2007, Vol. 15 Issue 3, p189
Academic Journal
Purpose: To investigate the relationship between age related macular degeneration (AMD) and serum lipid levels. Materials and Methods: Forty patients diagnosed with AMD and 30 age-matched healthy controls who were free of diabetes or hypercholesterolemia were included in the study. The patients in the study group were devided into exudative AMD (n=23) and nonexudative AMD (n=17) groups. The serum lipid levels of all patients were measured and the results were compared between all groups. Results: The total cholesterol levels of exudative AMD group were higher than the nonexudative AMD and the control groups, whereas there was no difference between the nonexudative AMD and control group cholesterol levels. There was no statistically significant difference in the serum trigliceride, very low density lipoprotein (VLDL)-cholesterol, high density lipoprotein (HDL)-cholesterol, total cholesterol/HDL-cholesterol, low density lipoprotein (LDL)-cholesterol levels between all the groups, but the HDL-cholesterol and LDL-cholesterol levels were markedly high in the exudative AMD group. Conclusion: High serum cholesterol levels are probably a risk factor in the development of exudative age related macular degeneration.


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