Should critically ill patients be routinely transfused to a normal haemoglobin level?

Markhorst, D. G.; Kneyber, M. C. J.
November 2007
Archives of Disease in Childhood;Nov2007, Vol. 92 Issue 11, p1038
Academic Journal
The article presents a case study on whether critically ill patients should be transfused to a normal hemoglobin level among children in Great Britain. Anemia is considered common among critically ill patients and may have multiple causes. It is suggested that hemoglobin concentration should be maintained at levels of at least 10 grams per deciliter in maintaining oxygen delivery. Study shows that transfusion decision tend to be driven by individual transfusion triggers rather than by specific physiological triggers or consensus. It was found out that the patients are at increased risk of death whether or not transfusions are prescribed.


Related Articles

  • Anemia during and at discharge from intensive care: the impact of restrictive blood transfusion practice. Walsh, Timothy S.; Lee, Robert J.; Maciver, Caroline R.; Garrioch, Magnus; MacKirdy, Fiona; Binning, Alexander R.; Cole, Stephen; McClelland, D. Brian // Intensive Care Medicine;Jan2006, Vol. 32 Issue 1, p100 

    Objective: To document the prevalence of anemia among patients admitted to intensive care (ICU) and, among survivors, at ICU discharge when restrictive transfusion practice was used.Design: This was an observational cohort study.Setting: Ten of the 26...

  • To Shake or Not to Shake. MUTHANA, FRANCES; ANDREWS, BILLY F. // Clinical Pediatrics;Apr1969, Vol. 8 Issue 4, p240 

    Determines whether shaking of the donor blood bottle during exchange transfusion can affect the infant's levels of hemoglobin and total protein. Claim that careful attention to agitation of donor blood during exchange transfusion corrects or partly corrects a child's anemia; Suggestion that when...

  • Managing anaemia in critically ill adults. Walsh, Timothy S.; Wyncoll, Duncan L. A.; Stanworth, Simon J. // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;9/11/2010, Vol. 341 Issue 7772, p547 

    The article discusses issues related to the management of anaemia in critically ill adults. It highlights uncertainties in the management of anaemia in critically ill patients and presents current evidence from observational studies and randomised trials. It enumerates several factors that...

  • Effect of Administering Recombinant Erythropoietin to Women with Postpartum Anemia: A Meta-analysis. Kotto-Kome, Anne C.; Calhoun, Darlene A.; Montenegro, Raul; Sosa, Roberto; Maldonado, Luis; Christensen, Robert D. // Journal of Perinatology;Jan2004, Vol. 24 Issue 1, p11 

    OBJECTIVES:: Recombinant erythropoietin (rEpo) has been administered to women with postpartum anemia in an attempt to accelerate their increase in hemoglobin concentration and reduce postpartum transfusions. However, it is not clear whether such an approach can be supported by evidence and...

  • Anemia and brain oxygen after severe traumatic brain injury. Oddo, Mauro; Levine, Joshua; Kumar, Monisha; Iglesias, Katia; Frangos, Suzanne; Maloney-Wilensky, Eileen; Roux, Peter // Intensive Care Medicine;Sep2012, Vol. 38 Issue 9, p1497 

    Purpose: To investigate the relationship between hemoglobin (Hgb) and brain tissue oxygen tension (PbtO) after severe traumatic brain injury (TBI) and to examine its impact on outcome. Methods: This was a retrospective analysis of a prospective cohort of severe TBI patients whose PbtO was...

  • Patient blood management is a win-win: a wake-up call. Spahn, D. R.; Theusinger, O. M.; Hofmann, A. // BJA: The British Journal of Anaesthesia;Jun2012, Vol. 108 Issue 6, p889 

    No abstract available.

  • Effect of a patient blood management programme on preoperative anaemia, transfusion rate, and outcome after primary hip or knee arthroplasty: a quality improvement cycle†‡. Kotzé, A.; Carter, L. A.; Scally, A. J. // BJA: The British Journal of Anaesthesia;Jun2012, Vol. 108 Issue 6, p943 

    Background There are few data on the associations between anaemia, allogeneic blood transfusion (ABT), patient blood management, and outcome after arthroplasty in the UK. National agencies nevertheless instruct NHS Trusts to implement blood conservation measures including preoperative anaemia...

  • Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy. Salhan, Sudha; Tripathi, Vrijesh; Singh, Rajvir; Gaikwad, Harsha S. // Anemia (20901267);2012, p1 

    Objectives. Anemia is a major public health problem throughout the world which assumes prominence in pregnant mothers. Patients with severe anemia continue to present themselves at term or in labor. This study was conducted to compare the improvements in hematological parameters of patients...

  • Economic burden of beta-thalassemia/Hb E and beta-thalassemia major in Thai children. Riewpaiboon, Arthorn; Nuchprayoon, Issarang; Torcharus, Kitti; Indaratna, Kaemthong; Thavorncharoensap, Montarat; Ubol, Bang-on // BMC Research Notes;2010, Vol. 3, p29 

    Background: Hemoglobin E beta-thalassemia (β-thalassemia/Hb E) has a variable severity, and the cost of treatment has not been well studied. The aim of this study was to analyze the societal cost of caring for children with β-thalassemias in Thailand. The study was designed as a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics