In neonates requiring intravascular volume resuscitation is the use of Gelofusine safe and efficacious?

Khashu, Minesh; Balasubramaniam, Velur
November 2007
Archives of Disease in Childhood;Nov2007, Vol. 92 Issue 11, p1037
Academic Journal
The article presents a case study on whether the use of Gelofusine is safe and efficacious in neonates requiring intravascular volume resuscitation in Great Britain. Study shows that the effects of Gelofusine or alternative volume expansion in preterm infants have been subjected to a systematic review including seven randomized controlled trials (RCTs). It was found out that Gelofusine has less antigenic properties and a lower chance of hypersensitivity reactions. Results indicate that there is no evidence to back Gelofusine's efficacy for use in volume expansion in neonates, though it is available and cheap, and less monitoring is required.


Related Articles

  • Patients with anaphylaxis in accident and emergency are not referred to specialised allergy services. El-Shanawany, Tariq; Seddon, Laura; Jolles, Stephen; Carne, Emily; Dowd, Hugo; Williams, Paul // Journal of Clinical Pathology;Apr2010, Vol. 63 Issue 4, p375 

    Allergy prevalence is reported to be increasing, and anaphylaxis represents the most severe end of the spectrum of allergic disease. UK data show a lifetime prevalence of anaphylaxis of 75.5 per 100 000, similar to epidemiological studies in the USA. There are approximately 20 deaths from...

  • The value of video and telephone assistance in mock resuscitations for persons with no training in cardiopulmonary resuscitation. Bingham, J.; Atkinson, P.; McNicholl, B.; Loane, M. // Journal of Telemedicine & Telecare;Mar1998 Supplement 1, Vol. 4, p104 

    This article presents a study which assessed the value of video and telephone assistance in mock resuscitations for persons with no training in cardiopulmunary resuscitation. The study looked at different methods of providing advice for cardiopulmonary resuscitation. In most developed countries...

  • Resus Sim 98.  // Internet Journal of Genomics & Proteomics;2003, Vol. 1 Issue 1, p11 

    ResusSim 98 is a PC-based simulator of Advanced Life Support (ALS) aimed at doctors, medical students, nurses, paramedics, and other health care personnel. A real-time ECG is shown on the screen along with pictures of the relevant resuscitation situation. The program provides the user with a...

  • Put breath in without passing out. Barnard, Keith // GP: General Practitioner;5/5/2003, p95 

    This article provides information related to a product used for resuscitation. One of the more unwelcome consequences of this dedication to one's calling is the need to carry out mouth-to-mouthresuscitation from time to time. The hapless subjects are frequently hirsute, and the beard or...

  • Damage control resuscitation: addressing trauma-induced coagulopathy. Duchesne, Juan C. // British Journal of Hospital Medicine (17508460);Jan2009, Vol. 70 Issue 1, p22 

    Damage control resuscitation attempts early, aggressive correction of trauma-induced coagulopathy in conjunction with interventions designed to achieve early surgical haemostasis and control of contamination. This article reviews the basis of damage control resuscitation and looks at...

  • Implementing a simplified neonatal resuscitation protocol-helping babies breathe at birth (HBB) -- at a tertiary level hospital in Nepal for an increased perinatal survival. Ashish KC; Målqvist, Mats; Wrammert, Johan; Verma, Sheela; Aryal, Dhan Raj; Clark, Robert; Naresh P KC; Vitrakoti, Ravi; Baral, Kedar; Ewald, Uwe // BMC Pediatrics;2012, Vol. 12 Issue 1, p159 

    Background: Reducing neonatal death has been an emerging challenge in low and middle income countries in the past decade. The development of the low cost interventions and their effective delivery are needed to reduce deaths from birth asphyxia. This study will assess the impact of a simplified...

  • Student tutors for hands-on training in focused emergency echocardiography -- a randomized controlled trial. Khl, Matthias; Wagner, Robert; Bauder, Markus; Fenik, Yelena; Riessen, Reimer; Lammerding-K”ppel, Maria; Gawaz, Meinrad; Fateh-Moghadam, Suzanne; Weyrich, Peter; Celebi, Nora // BMC Medical Education;2012, Vol. 12 Issue 1, p101 

    Background: Focused emergency echocardiography performed by non-cardiologists has been shown to be feasible and effective in emergency situations. During resuscitation a short focused emergency echocardiography has been shown to narrow down potential differential diagnoses and to improve patient...

  • Cardiopulmonary Resuscitation.  // Mayo Clinic Family Health Book;2003, p347 

    This article focuses on cardiopulmonary resuscitation (CPR), a lifesaving technique used in several emergency situations. Step-by-step instructions are provided on how to perform CPR on adults. The first thing one must do is to clear the airway, followed by breathing for the person. Information...

  • Gasping in Response to Basic Resuscitation Efforts: Observation in a Swine Model of Cardiac Arrest. Zuercher, Mathias; Ewy, Gordon A.; Otto, Charles W.; Hilwig, Ronald W.; Bobrow, Bentley J.; Clark, Lani; Chikani, Vatsal; Sanders, Arthur B.; Berg, Robert A.; Kern, Karl B. // Critical Care Research & Practice;2010, p1 

    Objective. To analyze the effect of basic resuscitation efforts on gasping and of gasping on survival. Methods. This is secondary analysis of a previously reported study comparing continuous chest compressions (CCC CPR) versus chest compressions plus ventilation (30:2 CPR) on survival. 64 swine...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics