TITLE

In neonates requiring intravascular volume resuscitation is the use of Gelofusine safe and efficacious?

AUTHOR(S)
Khashu, Minesh; Balasubramaniam, Velur
PUB. DATE
November 2007
SOURCE
Archives of Disease in Childhood;Nov2007, Vol. 92 Issue 11, p1037
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a case study on whether the use of Gelofusine is safe and efficacious in neonates requiring intravascular volume resuscitation in Great Britain. Study shows that the effects of Gelofusine or alternative volume expansion in preterm infants have been subjected to a systematic review including seven randomized controlled trials (RCTs). It was found out that Gelofusine has less antigenic properties and a lower chance of hypersensitivity reactions. Results indicate that there is no evidence to back Gelofusine's efficacy for use in volume expansion in neonates, though it is available and cheap, and less monitoring is required.
ACCESSION #
27607730

 

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