Effect of meningitis in infancy on school-leaving examination results

de Louvois, John; Halket, Sue; Harvey, David
November 2007
Archives of Disease in Childhood;Nov2007, Vol. 92 Issue 11, p959
Academic Journal
Objectives: To determine whether having had meningitis in infancy adversely affects academic achievement at age 16. Methods: A case-control study in England and Wales of 461 teenagers who had bacterial meningitis in infancy and 289 GP matched controls recruited when the index cases were aged 5. Outcome measures: Comparison between index cases and controls of the type of school attended; the number of GCSE examinations attempted; the number of examinations passed (grades A*-C) and achievement in five key subjects. Assessment of examination results according to the age at which meningitis occurred. The effect of meningitis-associated disability on GCSE results. Results: 36/461 (7.8%) index cases compared with none of the controls were in special schools. Significantly more index cases (117/461 (25.4%)) than controls (19/289 (6.6%)) did not pass any GCSE examinations. Significantly more index cases (184/385 (47.8%)) than controls (59/232 (25.4%)) attending comprehensive schools failed to achieve the national educational standard of five passes at grade C. Pupils attending comprehensive schools who did not have meningitis-associated disability also passed significantly fewer GCSE examinations than the controls. The age at which meningitis had occurred was not associated with subsequent academic achievement. Conclusions: After meningitis in infancy a quarter of survivors failed to pass any GCSE examinations; nearly half of those attending state schools did not attain the national educational standard. "Healthy" survivors of bacterial meningitis in infancy pass significantly fewer GCSE examinations than the controls. All cases of bacterial meningitis in infancy should have a full postinfection assessment and continuing supervision.


Related Articles

  • To Tap or Not To Tap . . . What Are the Best Indicators for Performing a Lumbar Puncture in an Outpatient Child? Gururaj, V. J.; Russo, Raymond M.; Allen, John E.; Herszkowicz, Rozalia // Clinical Pediatrics;Aug1973, Vol. 12 Issue 8, p488 

    A survey of the signs and symptoms of 709 children subjected to lumbar puncture on the suspicion of meningitis did not permit construction of a pattern which could identify the existence of meningitis in a suspected case. The predictive value for the symptoms of lethargy, headache, and...

  • Ocular Manifestations of Meningitis in Children. Chaudhary, M.; Shah, D. N.; Sharma, P. R. // Journal of Nepal Paediatric Society;May-Aug2012, Vol. 32 Issue 2, p136 

    Introduction: Meningitis is the most common central nervous system disease affecting children leading to focal neurological deficits and various oculovisual anomalies including blindness in children. The objective of this study was to evaluate the oculovisual anomalies occurring in Nepalese...

  • Single Nucleotide Polymorphisms in TLR9 Are Highly Associated with Susceptibility to Bacterial Meningitis in Children. Sanders, Marieke S.; van Well, Gijs Th. J.; Ouburg, Sander; Lundberg, Patric S. J.; van Furth, A. Marceline; MorrĂ©, Servaas A. // Clinical Infectious Diseases;2/15/2011, Vol. 52 Issue 4, p475 

    Background. Bacterial meningitis (BM) is a severe infection mainly caused by Streptococcus pneumoniae and Neisseria meningitidis (NM). However, genetically determined susceptibility to develop severe infections by these microorganisms is variable between individuals. Toll-like receptor 9 (TLR9)...

  • Tobacco smoke exposure and meningococcal disease risk. Sadovsky, Richard // American Family Physician;6/1/1998, Vol. 57 Issue 11, p2848 

    Focuses on the importance of the Neisseria meningitidis which causes the bacterial sepsis and meningitis in children. Information of an important strategy for preventing meningococcal disease; Reference to the mechanism by which the tobacco smoke increasing the risk of meningococcal disease.

  • Fatal tuberculous meningitis caused by immune restoration disease. Huttner, Hagen; Kollmar, Rainer; Hug, Andreas; Meisel, Fabian; Kress, Bodo; Schwab, Stefan // Journal of Neurology;Dec2004, Vol. 251 Issue 12, p1522 

    Discusses a case of fatal tuberculous meningitis caused by immune restorate disease. Pathophysiology; Treatment options.

  • Meningitis due to Escherichia Coli 0126:B16. Zoumboulakis, Dimitri; Karaboula, Katherine; Albanis, Vlassis; Kiossoglou, Kosmas A. // Clinical Pediatrics;Oct1972, Vol. 11 Issue 10, p603 

    Focuses on meningitis due to Escherichia coli 0126:B16. Discussion of a fatal case in a 14-year-old girl.

  • Enhanced surveillance of epidemic meningococcal meningitis in Africa: a three-year experience.  // Weekly Epidemiological Record;9/16/2005, Vol. 80 Issue 37, p313 

    The article discusses epidemic meningococcal meningitis in Africa. Meningococcal meningitis is a bacterial infection of the meninges, the thin lining that surrounds the brain and spinal cord, whose common symptoms are sudden onset of headache, high fever, stiff neck and sensitivity to light. The...

  • Meningococcal disease in the African meningitis belt.  // Weekly Epidemiological Record;3/7/2008, Vol. 83 Issue 10, p90 

    The article focuses on the meningococcal disease activity in the African meningitis belt, the area at sub-Saharan Africa that stretches from Senegal in the west to Ethiopia in the east. The levels of meningitis activity were 29 percent lower than what was reported in 2007. According to the...

  • Surgical Aspects of Nontuberculous Bacterial Meningitis in Infancy and Childhood. Adeloye, Adelola; Oyedeji, G. A. // Clinical Pediatrics;Oct1973, Vol. 12 Issue 10, p589 

    At the University College Hospital, Ibadan, Nigeria, congenital malformations of the central nervous system were important predisposing factors to meningitis. Among 80 patients who survived the acute illnes, the main complications encountered, in order of frequency, were hydrocephalus (12),...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics