Necrobiosis lipoidica diabeticorum

Körber, Andreas; Dissemond, Joachim
December 2007
CMAJ: Canadian Medical Association Journal;12/4/2007, Vol. 177 Issue 12, p1498
Academic Journal
The article discusses the origin and treatment strategies of necrobiosis lipodica diabeticorum. The disease was described as a chronic granulomatous dermatitis with no known cause. It commonly develops among patients aged 30-40 years old and has a female-male ratio of 3:1. The disease, which is associated with Chrohn's disease, ulcerative colitis and sadarcoidosis also develops in patients with diabetes. It usually appears as yellow-red plaques with telangiectatic vessels, central atrophy and raised violet-coloured edges on the shins and the back of the hands. Therapeutic options include glucocorticoids or psoralen plus ultraviolet A photochemotherapy, while new treatment strategies include cyclosporin A and infliximab.


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