Pulmonary actinomycosis complicating infliximab therapy for Crohn's disease

Cohen, R. D.; Bowie, W. R.; Enns, R.; Flint, J.; Fitzgerald, J. M.
November 2007
Thorax;Nov2007, Vol. 62 Issue 11, p1013
Academic Journal
The use of anti-tumour necrosis factor (TNF) agents has expanded significantly over the past few years, particularly for rheumatological diseases and Crohn's disease. A number of associated opportunistic infections have been observed as a result of suppression of T cell-mediated immunity, the most frequent being tuberculosis. We report the first case of pulmonary actinomycosis in a patient receiving regular infusions of infliximab, an anti-TNF agent, for Crohn's disease.


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