Fourth ventricular medullomyoblastoma: A case report with review of literature

Patel, P.; S., Annapurneswari; Ghosh, S.
July 2007
Journal of Pediatric Neurosciences;Jul-Dec2007, Vol. 2 Issue 2, p82
Academic Journal
Medullomyoblastoma (MMB) is a rare embryonal cerebellar neoplasm with both primitive neuroectodermal and striated muscle components. It occurs exclusively in children. It typically arises from the cerebellar vermis. There are only 54 case reports in the published literature. We report an additional case of a 7-year-old boy with fourth ventricular MMB that is unique in its site of origin, intratumoral hemorrhage and calcification.


Related Articles

  • Medulloblastoma brain tumor study demonstrates that presence of ERBB2 protein may signify resistance to treatment.  // PharmaWatch: Cancer;April 2004, Vol. 3 Issue 4, p22 

    Discusses a pilot study in Memphis, Tennessee, which demonstrated that by detecting the presence of a protein called ERBB2 in tumor samples, doctors might be able to predict which children with medulloblastoma require more intensive care. Demonstration that samples can be rapidly delivered to a...

  • Large cell medulloblastoma with myogenic and melanotic differentiation: a case report with molecular analysis. Arie Perry; Mark Edgar // Journal of Neuro-Oncology;Jun2008, Vol. 88 Issue 2, p193 

    Abstract  We present a case of large cell medulloblastoma with myogenic and melanotic differentiation arising in the cerebellar vermis of a 2-year-old boy and following an aggressive clinical course. Histologic and immunohistochemical features of this tumor include primitive neuronal,...

  • Bilateral Cerebellar Medulloblastomas: A Case Report And Review Of Literature. Velho, Vernon; Palande, Deepak; Kakani, Anand; Mally, Rahul; Ghodgaonkar, Pranav; Jaiswal, Amit // Internet Journal of Neurosurgery;2008, Vol. 5 Issue 1, p8 

    Medulloblastomas are common midline posterior fossa tumors in children, accounting for almost 30% of all pediatric brain tumors. In adults these tumors occur in the cerebellar hemisphere. Medulloblastomas occurring bilaterally in an adult patient is very rare. Present article includes a case...

  • Inconsistent terminology for cerebellar mutism. Thomale, Ulrich-Wilhelm; Driever, Pablo // Child's Nervous System;May2013, Vol. 29 Issue 5, p717 

    A response from the authors of the article "Fronto-cerebellar fiber tractography in pediatric patients following posterior fossa tumor surgery" in the 2012 issue is presented.

  • Supratentorial Leptomeningeal Metastasis of a Medulloblastoma Without Cerebellar Tumor Recurrence. Gerlach, R.; Kieslich, M.; van de Nes, J.; Galow, W.; Seifert, V. // Acta Neurochirurgica;Feb2002, Vol. 144 Issue 2, p201 

    Summary. The authors report on a 15-year-old girl presenting with headache and nausea. Cranial magnetic resonance imaging (MRI) showed a diffuse leptomeningeal contrast enhancement 5 years after resection of a posterior fossa medulloblastoma followed by radio- and chemotherapy. A left frontal...

  • Medulloblastomas: New directions in risk stratification. Sarkar, Chitra; Deb, Prabal; Sharma, Mehar Chand // Neurology India;Mar2006, Vol. 54 Issue 1, p16 

    Medulloblastomas (MBs) are the most common malignant brain tumors in children. Current therapeutic approaches combine surgery, radiotherapy, and chemotherapy. Although, there has been significant improvement in long-term survival rates, the tumor remains incurable in about a third of patients...

  • Developmental and oncogenic effects of Insulinlike Growth Factor-I in Ptc1+/- mouse cerebellum. Tanori, Mirella; Santone, Melissa; Mancuso, Mariateresa; Pasquali, Emanuela; Leonardi, Simona; Majo, Vincenzo Di; Rebessi, Simonetta; Saran, Anna; Pazzaglia, Simonetta // Molecular Cancer;2010, Vol. 9, p53 

    Background: Medulloblastoma is amongst the most common malignant brain tumors in childhood, arising from neoplastic transformation of granule neuron precursors (GNPs) of the cerebellum via deregulation of pathways involved in cerebellar development. Deregulation of the Sonic hedgehog/Patched1...

  • Polycomb genes expression as a predictor of poor clinical outcome in children with medulloblastoma. Zakrzewska, Magdalena; Zakrzewski, Krzysztof; Grešner, Sylwia M.; Piaskowski, Sylwester; Zalewska-Szewczyk, Beata; Liberski, Paweł P. // Child's Nervous System;Jan2011, Vol. 27 Issue 1, p79 

    Introduction: Medulloblastoma is the most frequent type of embryonal tumor in the pediatric population, accounting for 20-25% of all brain tumors in children. Recently, the suspected contribution of the Polycomb group (PcG) genes in medulloblastoma development was described. PcG genes play an...

  • Genomic imbalances in childhood medulloblastoma by comparative genomic hybridization. Keser, Ibrahim; Burckhardt, Elisabeth; Tunali, Nurdan; Alkan, Mualla // Turkish Journal of Cancer;Oct2003, Vol. 33 Issue 4, p177 

    We used comparative genomic hybridization (CGH) technique to identify the genetic changes in 12 childhood medulloblastoma samples obtained from archived paraffin-embedded tissues belonging to children (0.7-15 years-old) using double step degenerate oligonucleotide-primed polymerase chain...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics