Congenital glioblastoma multiforme: A case report and review of literature

Kasliwal, Manish K.; Gupta, Deepak K.; Mahapatra, Ashok K.; Sharma, Mehar C.
July 2007
Journal of Pediatric Neurosciences;Jul-Dec2007, Vol. 2 Issue 2, p69
Academic Journal
Congenital brain tumors are very rare neoplasms. The diagnosis of glioblastoma multiforme in a newborn infant is a rarity. Prognosis of congenital glioblastoma has been uniformly fatal with most of the cases reported in literature having a very short survival in spite of all modalities of treatment. The authors report a case of congenital glioblastoma involving the pan right cerebral hemisphere in a two month-old infant who expired six months after tumor decompression. Literature is reviewed in light of the present case and various treatment modalities for this rare tumor are highlighted.


Related Articles

  • Perinatal (fetal and neonatal) astrocytoma: a review. Isaacs, Hart // Child's Nervous System;Nov2016, Vol. 32 Issue 11, p2085 

    Introduction: The purpose of this review is to document the various types of astrocytoma that occur in the fetus and neonate, their locations, initial findings, pathology, and outcome. Data are presented that show which patients are likely to survive or benefit from treatment compared with those...

  • ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an 'integrated' diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. Reuss, David; Sahm, Felix; Schrimpf, Daniel; Wiestler, Benedikt; Capper, David; Koelsche, Christian; Schweizer, Leonille; Korshunov, Andrey; Mittelbronn, Michel; Platten, Michael; Wick, Wolfgang; Pfister, Stefan; Deimling, Andreas; Jones, David; Hovestadt, Volker; Schittenhelm, Jens; Herold-Mende, Christel; Unterberg, Andreas; Weller, Michael // Acta Neuropathologica;Jan2015, Vol. 129 Issue 1, p133 

    Diffuse gliomas are represented in the 2007 WHO classification as astrocytomas, oligoastrocytomas and oligodendrogliomas of grades II and III and glioblastomas WHO grade IV. Molecular data on these tumors have a major impact on prognosis and therapy of the patients. Consequently, the inclusion...

  • Congenital factor XIII deficiency in a neonate. Francis, John; Ford, Peter // British Medical Journal;12/2/1978, Vol. 2 Issue 6151, p1532 

    Presents a case report on congenital factor XIII deficiency among neonates in Great Britain. Background history of the disease; Symptoms of the disease; Complications of the disease.

  • Cystic hygroma and lymphangioma: associated findings, perinatal outcome and prognostic factors in live-born infants. Gedikbasi, Ali; Gul, Ahmet; Sargin, Akif; Ceylan, Yavuz // Archives of Gynecology & Obstetrics;Nov2007, Vol. 276 Issue 5, p491 

    Objectives: We aimed to determine associated ultrasonographic findings, chromosome abnormalities and the prognostic factors of cystic hygromas in live-born infants. Methods: We reported a series of 57 cystic hygroma cases, who were diagnosed in the first and the second...

  • 2012 American Society of Clinical Oncology Annual Meeting: Revised glioblastoma classification should improve patient care.  // Biomedical Market Newsletter;5/25/2012, Vol. 21, p1 

    The article informs that a new system is being used by the radiation oncology researchers for the prognosis of glioblastoma which has been incorporated with molecular biomarkers and clinical variables.

  • Miracle kid. Franks, Lucinda // New Yorker;05/17/99, Vol. 75 Issue 11, p68 

    No abstract available.

  • Cor triatriatum sinister presenting in the adult as mitral stenosis. Slight R D; Nzewi O C; Sivaprakasam R; Mankad P S // Heart;Oct2003, Vol. 89 Issue 10, pe26 

    Cor triatriatum sinister is a rare congenital defect in which the left atrium is divided by a fibromuscular membrane into two distinct chambers. Classically, patients present in infancy although in some cases they remain asymptomatic until adulthood. The clinical features on presentation can...

  • Complete Congenital Sternal Cleft Associated with Pectus Excavatum. Sarper, Alpay; Oz, Necdet; Arslan, Gokhan; Demircan, Abid // Texas Heart Institute Journal;2002, Vol. 29 Issue 3, p206 

    We report herein a rare case of complete congenital sternal cleft (absent sternum) and anterior pericardial defect in association with pectus excavatum. In neonates with absent sternum, the sternal bars can be easily approximated by simple suture, due to the flexibility of the cartilaginous...

  • Translational genetics: Whole-genome sequencing diagnostics for newborns. Flintoft, Louisa // Nature Reviews Genetics;Nov2012, Vol. 13 Issue 11, p758 

    The article discusses research on the use of whole-genome sequencing (WGS) in the diagnosis of genetic disorders in newborn infants, which references the study "Rapid whole-genome sequencing for genetic-disease diagnosis in neonatal intensive care units," by C. J. Saunders in the 2012 issue.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics