TITLE

Early Accuracy in New Drug Safety Analysis

AUTHOR(S)
Yanowitz, Frank G.
PUB. DATE
October 2007
SOURCE
Applied Clinical Trials;Oct2007 Supplement, p12
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the methodologies for evaluating the risk of noncardiovascular drugs for Torsade de pointes and other life-threatening arrhythmias. In this paper, limitations in guidelines are considered and recommendations for further study are reviewed. Torsade de Pointes is a ventricular tachycardia that has its origin in patients with hereditary or acquired long QT syndrome. Arrhythmia degenerates into ventricular fibrillation leading to syncope.
ACCESSION #
27063460

 

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