Celecoxib combined with esomeprazole prevented recurrent ulcer bleeding in patients with previous NSAID- induced ulcer bleeding: COMMENTARY

Katz, Philip O.
September 2007
ACP Journal Club;Sept/Oct2007, Vol. 147 Issue 2, p38
Academic Journal
The article reports on prevention of recurrent ulcer bleeding in patients with previous NonSteroidal AntiInflammatory Drug (NSAID)- induced ulcer bleeding through treatment with combination of celecoxib and esomeprazole. It reports on higher occurrence of GastroIntestinal (GI) complications in old patients who have had prior GI bleeding or ulcer and take NSAIDs. A study has been discussed to fortify that coxib monotherapy alone isn't enough to prevent GI injury in high-risk patients.


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