TITLE

Melioidosis: an under-diagnosed entity in western coastal India: a clinico-microbiological analysis

AUTHOR(S)
Vidyalakshmi, K.; Shrikala, B.; Bharathi, B.; Suchitra, U.
PUB. DATE
July 2007
SOURCE
Indian Journal of Medical Microbiology;Jul2007, Vol. 25 Issue 3, p245
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Clinico-microbiological analysis of a series of 25 patients with culture proven melioidosis was done. All patients came from the coastal regions of Kerala and Karnataka and presented between June 2005 to July 2006. They were analysed with respect to clinical presentation, occupation, epidemiology and microbiological features. No single presenting clinical feature was found to be typical of melioidosis. The disease was found to mimic a variety of conditions, including tuberculosis and malignancy. Burkholderia pseudomallei was isolated from blood, sputum, pus, urine, synovial, peritoneal and pericardial fluids. Diabetes mellitus was the most common predisposing factor and 80% of the cases presented during the Southwest monsoon (June to September). It is probable that melioidosis is highly prevalent in western coastal India and yet, greatly underestimated. Better awareness, both among clinicians and microbiologists, coupled with improved diagnostic methods to allow early diagnosis and hence early treatment, will significantly reduce the morbidity and mortality associated with this disease.
ACCESSION #
26916670

 

Related Articles

  • Melioidosis in Odisha: A clinico-microbiological and epidemiological description of culture-confirmed cases over a 2-year period. Behera, Bijayini; Mohanty, Srujana; Mahapatra, Ashoka; Hallur, Vinay Kumar; Mishra, Baijayantimala; Dey, Anupam; Kumar, Rajesh; Mishra, Tushar K.; Sasmal, Prakash K.; Sinha, Mithilesh; Mohapatra, Prasant R.; Panigrahi, Manoj K.; Preetam, C.; Das, Rashmi Ranjan // Indian Journal of Medical Microbiology;Jul-Sep2019, Vol. 37 Issue 3, p430 

    Melioidosis is an emerging infectious disease in India mostly reported from South-western coastal Karnataka and North-eastern Tamil Nadu. We speculate the existence of another major hidden focus in Odisha, one of the eastern coastal states. The clinico-epidemiological features of 47...

  • The clinical profile and predictors of mortality in patients with melioidosis in South India. Chrispal, Anugrah; Rajan, Sudha Jasmine; Sathyendra, Sowmya // Tropical Doctor;Jan2009, Vol. 40 Issue 1, p36 

    Melioidosis is an underdiagnosed and underreported disease in India with protean clinical manifestations. Mortality in this study population was 17%. The predominant risk factor for melioidosis was diabetes mellitus. Multifocal disease was present in 66% and pulmonary involvement in 61% of...

  • Acute pulmonary melioidosis in a child: A case report and review of literature. Boruah, Deb K.; Prakash, Arjun; Bora, Reeta; Buragohain, Lemanstar // Indian Journal of Radiology & Imaging;Nov2013, Vol. 23 Issue 4, p310 

    Melioidosis is a rare potentially fatal infection caused by the bacterium Burkholderia pseudomallei, which is endemic in Southeast Asia and Northern Australia and an emerging pathogen in India. It is a largely under-diagnosed disease and an imitator of tuberculosis, both clinically and...

  • Pediatric Melioidosis in Southern India. MUKHOPADHYAY, CHIRANJAY; ESHWARA, VANDANA K.; KINI, PUSHPA; BHAT, VINOD // Indian Pediatrics;Aug2015, Vol. 52 Issue 8, p711 

    Melioidosis in children is increasingly detected from the coastal region of Southern India during monsoon. We present 11 cases of melioidosis, ranging from localized to disseminated, treated successfully, barring one death. It calls for awareness and upgrading laboratory facilities for better...

  • Septicaemic Melioidosis: Case Report from a Non-Endemic Area. SOOD, SMITA; SINGH KHEDAR, RAGHUVIR; HK JOAD, SHABBAR; GUPTA, RAJEEV // Journal of Clinical & Diagnostic Research;Dec2014, Vol. 8 Issue 12, p1 

    Melioidosis is a clinically diverse disease caused by the facultative intracellular Gram-negative bacterium, Burkholderia pseudomallei. In recent times melioidosis has been increasingly reported in India especially from the southern and coastal states. We report a fatal case of septicaemic...

  • Melioidosis and pulmonary tuberculosis co-infection in a diabetic. Shetty, Anup Kumar; Boloor, Rekha; Sharma, Vishnu; Keshava Bhat, Ganesh Hosahithlu // Annals of Thoracic Medicine;Apr-Jun2010, Vol. 5 Issue 2, p113 

    Burkholderia pseudomallei is the causative agent of melioidosis. It is endemic in South East Asian countries and North Australia. Sporadic cases of melioidosis have been reported from several parts of South India. Melioidosis may manifest as chronic pneumonia mimicking tuberculosis and generally...

  • Cholera like expression of Escherichia coli: An outbreak investigation from Central India. Joshi, Ankur; Kale, Saket // International Journal of Medicine & Public Health;Jul2013, Vol. 3 Issue 3, p151 

    Background: This paper investigates a swift gastrointestinal outbreak in central India and further explores environmental, agent, and host interactions culminating into outbreak. Materials and Methods: Epidemic investigation was launched as per the standard protocol laid by Center for Disease...

  • Melioidosis Presenting as Fever and Jaundice: A Rare Presentation. Tyagi, Pankaj; Shah, Vinit; Sharma, Praveen; Bansal, Naresh; Singla, Vikas; Kumar, Ashish; Arora, Anil // Experimental & Clinical Hepatology;Jun2014, Vol. 4 Issue 2, p172 

    Melioidosis caused by the environmental Gram-negative bacillus Burkholderia pseudomallei is endemic in northern Australia and Southeast Asia and is being described increasingly from south and west coastal regions of India. Melioidosis is known to have high mortality (14-50%) and the risk factors...

  • Unravelling the Molecular Epidemiology and Genetic Diversity among Burkholderia pseudomallei Isolates from South India Using Multi-Locus Sequence Typing. Tellapragada, Chaitanya; Kamthan, Aayushi; Shaw, Tushar; KE, Vandana; Kumar, Subodh; Bhat, Vinod; Mukhopadhyay, Chiranjay // PLoS ONE;12/19/2016, Vol. 11 Issue 12, p1 

    There is a slow but steady rise in the case detection rates of melioidosis from various parts of the Indian sub-continent in the past two decades. However, the epidemiology of the disease in India and the surrounding South Asian countries remains far from well elucidated. Multi-locus sequence...

  • Gujarat honors the Whale Shark.  // South Asian Post;2/18/2010, p19 

    The article reports that India's western coastal state of Gujarat will celebrate the Whale Shark Day in December 2010.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics