TITLE

Sustained fever resolved promptly after total thyroidectomy due to huge Hashimoto's fibrous thyroiditis

AUTHOR(S)
Sumihisa Kubota; Fumio Matsuzuka; Hidemi Ohye; Eijun Nishihara; Takumi Kudo; Mitsuru Ito; Takeshi Arishima; Shuji Fukata; Mitsuyoshi Hirokawa; Nobuyuki Amino; Akira Miyauchi
PUB. DATE
February 2007
SOURCE
Endocrine (1355008X);Feb2007, Vol. 31 Issue 1, p88
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We encountered a 55-year-old female patient with Hashimoto's thyroiditis who showed persistent fever, and could not find any source of fever other than the large nontender goiter. Her fever continued with positive CRP for 6 months. Although we did not assume that the inflammation was related to Hashimoto's thyroiditis, total thyroidectomy was performed for cosmetic reasons; however, fever was resolved immediately after thyroidectomy. Pathological diagnosis was Hashimoto's chronic thyroiditis. Immunohistochemical staining showed that the follicular cells were positive for IL-1alpha, IL-1beta, and TNF-alpha. We believed that fever was induced by inflammatory cytokines produced in thyroid. The case indicated that Hashimoto's thyroiditis with nontender goiter could cause idiopathic fever.
ACCESSION #
26845298

 

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