HIV-1 Infection and the Kidney: An Evolving Challenge in HIV Medicine
- A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders. Besbas, N.; Karpman, D.; Landau, D.; Loirat, C.; Proesmans, W.; Remuzzi, G.; Rizzoni, G.; Taylor, C. M.; Van de Kar, N.; Zimmerhackl, L. B. // Kidney International;Aug2006, Vol. 70 Issue 3, p423
The diagnostic terms hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are based on historical and overlapping clinical descriptions. Advances in understanding some of the causes of the syndrome now permit many patients to be classified according to etiology. The...
- Functional analyses indicate a pathogenic role of factor H autoantibodies in atypical haemolytic uraemic syndrome. Strobel, Stefanie; Hoyer, Peter F.; Mache, Christoph J.; Sulyok, Endre; Liu, Wei-shih; Richter, Heiko; Oppermann, Martin; Zipfel, Peter F.; Józsi, Mihály // Nephrology Dialysis Transplantation;Jan2010, Vol. 25 Issue 1, p136
Background. Atypical haemolytic uraemic syndrome (aHUS) is associated with defective complement regulation. Recently, an autoimmune aHUS form has been described that is associated with complement factor H (CFH) autoantibodies. The aim of this study was to address the pathologic relevance of CFH...
- Shiga toxin-1 affects nitric oxide production by human glomerular endothelial and mesangial cells. Maroeska te Loo, D.; Monnens, Leo; van der Velden, Thea; Karmali, Mohammed; van den Heuvel, Lambertus; van Hinsbergh, Victor // Pediatric Nephrology;Dec2006, Vol. 21 Issue 12, p1815
Acute renal failure hallmarks the pathogenesis of the epidemic form of hemolytic uremic syndrome (D+HUS), which is caused by E. coli strains that produce Shiga-like toxin (Stx). In this study, we investigated the influence of Stx-1 on nitric oxide (NO) production by human glomerular...
- A rare cause of the pulmonary-renal syndrome: a case of atypical haemolytic-uraemic syndrome complicated by pulmonary haemorrhage. Derebail, Vimal K.; Parikh, Palak; Jennette, J. Charles; Kshirsagar, Abhijit V. // NDT Plus;Dec2008, Vol. 1 Issue 6, p417
Pulmonary haemorrhage is a potentially life-threatening event that may occur in patients with pulmonary-renal syndromes. These syndromes have typically been thought to occur in small-vessel vasculitides, such as ANCA-mediated disease, Goodpasture's disease and other autoimmune conditions...
- Peginterferon-Î±-2a. // Reactions Weekly;4/9/2011, Issue 1346, p33
The article describes the case of a 43-year-old woman who developed thrombotic thrombocytopenic purpura (TTP) following peginterferon-Î±-2a treatment.
- Light at the end of the TUNEL: HIV-associated thrombotic microangiopathy. Alpers, Charles E. // Kidney International;Jan2003, Vol. 63 Issue 1, p385
Presents a case of HIV-associated thrombotic microangiopathy. Renal biopsy microscopic description; Pathogenesis; Therapy.
- Thrombotic Thrombocytopenic Purpura in a Patient Who Subsequently Developed the Acquired Immunodeficiency Syndrome (AIDS). Botti, Anthony C.; Hyde, Phyllis; DiPillo, Frank // Annals of Internal Medicine;8/1/88, Vol. 109 Issue 3, p242
Reports the case of a patient with thrombotic thrombocytopenic purpura who developed AIDS. Admission laboratory data of the patient; Results of medical tests administered in the patient; Need for an HIV antibody test in patients with thrombotic thrombocytopenic purpura at diagnosis and before...
- HIV associated thrombotic microangiopathy. S. Ahmed; R.K. Siddiqui; A.K. Siddiqui; S.A. Zaidi; J. Cervia // Postgraduate Medical Journal;Sep2002, Vol. 78 Issue 923, p520
Thrombotic microangiopathy (TMA) is a known complication of HIV infection. Endothelial cell injury appears to be the primary event causing platelet activation and deposition in the microvasculature. Direct cytopathic roles of HIV as well as other factors such as malignancy, drugs, and infectious...
- Thrombic microangiopathy and acute renal failure associated with arteriography. Fairley, Stephen; U'Hile, Benno // British Medical Journal (Clinical Research Edition);10/11/1986, Vol. 293 Issue 6552, p922
Examines the thrombotic microangiopathy and renal failure associated with arteriography. Mechanism of acute renal failure following administration of contrast media; Treatment of patients with acute renal failure; Causes of thrombotic microangiopathy.