Oral Anticoagulant + Antiplatelet Therapy = Danger

September 2007
Travel Medicine Advisor;Sep2007, Vol. 17 Issue 9, p1
The article discusses a study on the effectiveness of adding an anticoagulant to aspirin in patients with peripheral artery disease (PAD). It notes that antiplatelet drugs are commonly prescribed for such patients. According to the findings, the combination of the drugs can be dangerous. The researchers conclude that an oral anticoagulant with antiplatelet therapy was associated with an increase in life-threatening bleeding.


Related Articles

  • Dual antiplatelet therapy with clopidogrel and aspirin. Sullivan, Joshua; Amarshi, Naseem // American Journal of Health-System Pharmacy;6/15/2008, Vol. 65 Issue 12, p1134 

    Purpose. Dual antiplatelet therapy with clopidogrel and aspirin is reviewed. Summary. Several studies have evaluated the effectiveness of clopidogrel, aspirin, or the combination of these agents in a variety of patient populations. The results of these studies have helped determine the role of...

  • Is aspirin plus dipyridamole as effective as clopidogrel for preventing recurrent stroke?  // Journal of Family Practice;Dec2008, Vol. 57 Issue 12, p781 

    The article provides facts on the idea that taking aspirin along with dipyridamole would be effective as taking clopidrogel for preventing recurrent stroke in the U.S. It notes that the combination of asprin and dipyridamole are similarly effective to clopidrogel. However, it connotes that...

  • Anticoagulants in venous thromboembolism. Fennerty, A.; Campbell, I.A. // BMJ: British Medical Journal (International Edition);11/19/88, Vol. 297 Issue 6659, p1285 

    Examines the effects of anticoagulants in venous thromboembolism. Use of heparin and warfarin to treat deep vein thrombosis and pulmonary embolism; Influence of heparin in the incidence of hemorrhage; Relation between hemorrhage incidence and prothrombin time.

  • Aspirin reduces non-fatal stroke in patients with peripheral artery disease.  // Australian Journal of Pharmacy;Jan2010, Vol. 91 Issue 1076, p63 

    The article discusses the result of a study which examines the effects of aspirin in patients with peripheral artery disease. The study analyzes the data from 5,269 patients and shows that aspirin therapy was associated with a reduction in the secondary outcome of non-fatal stroke and reduces...

  • Antithrombotic treatment for peripheral arterial disease. Hackam, Daniel G.; Eikelboom, John W. // Heart;Mar2007, Vol. 93 Issue 3, p303 

    Context: Patients with peripheral arterial disease (PAD) bear a substantial risk for vascular events in the coronary, cerebral and peripheral circulations. In addition, this disorder is associated with a systemic milieu characterised by ongoing platelet activation and heightened thrombogenesis....

  • Needle Electromyograph Hemorrhagic Risks and Complications. Rubin, Michael // Neurology Alert;Dec2008, Vol. 27 Issue 4, p30 

    IS THERE AN INCREASED RISK OF HEMATOMA FORMATION following needle electromyography (EMG) in patients on aspirin, clopidogrel, or warfarin? To address this question, adult patients undergoing EMG of the tibialis anterior muscle, as part of a routine lower extremity EMG, were enrolled in a...

  • Aspirin.  // Reactions Weekly;6/13/2009, Issue 1256, p9 

    The article describes the case of a 67-year-old man with unrecognised platelet dysfunction who experienced spontaneous haemorrhages during antiplatelet drug therapy with aspirin. The patient's medical history and treatment regimen are discussed. An overview of the findings from diagnostic tests...

  • Massive pontine hemorrhagic transformation associated with an anticoagulant for basilar artery occlusion. Ming-Chang Hsiao; Jiann-Der Lee; Meng Lee; Hsu-Huei Weng // Neurology India;Dec2006, Vol. 54 Issue 4, p431 

    The article discusses the case of a 66-year-old male patient who developed massive pontine hemorrhagic transformation following anticoagulant for basilar artery occlusion (BAO). Computed tomography images of the patient's brain showed infarction over bilateral thalami and occipital lobes....

  • Vascular viewpoint. Anand, S.S. // Vascular Medicine;2001, Vol. 6 Issue 1, p61 

    Question: Are oral anticoagulants (target INR 3.0–4.5) more effective than aspirin (80 mg) in the prevention of infrainguinal bypass-graft occlusion? Population: Patients who required infrainguinal bypass graft surgery (venous or synthetic grafts) for obstructive arterial disease. Design...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics