Intestinal Gas Retention in Patients with Idiopathic Slow-Transit Constipation

Ana Hernando-Harder; Andreas Franke; Thilo Wedel; Martina Böttner; Heinz-Juergen Krammer; Manfred Vincenz Singer; Hermann Harder
October 2007
Digestive Diseases & Sciences;Oct2007, Vol. 52 Issue 10, p2667
Academic Journal
Abstract  Patients with slow-transit constipation (STC) have delayed colonic transit for solid und liquid bowel contents but intestinal gas handling has not been studied so far. Different nutrients influence motor and sensory gut function. We hypothesized that, in patients with STC, alteration of regulatory mechanisms may result in impaired intestinal gas dynamics. On 3 separate days, validated gas challenge was performed in 10 STC patients and 10 volunteers during duodenal saline, lipids, or intravenous glucose. During saline only 60% � 8% of gas was cleared by STC patients after 60-min gas infusion, vs. 91% � 2% by controls (P 


Related Articles

  • CONSTIPATION--a common problem. Richards, Sara // Practice Nurse;9/10/2004, Vol. 28 Issue 4, p42 

    Provides information on risks associated with constipation. Factors that should be considered before the treatment for constipation can be prescribed; Causes of constipation; Assessment of constipation in babies and children; General treatment options.

  • Three steps to better management of constipation. Merli, Geno J.; Graham, Mark G.; D'Epiro, Peter // Patient Care;Jun2003, Vol. 37 Issue 6, p37 

    Presents a three-step management plan for the management of constipation. Procedures for evaluation; Maintenance of adequate hydration and fiber intake; Pharmacologic therapy to maintain colonic function; Recommended colonic irritants and stimulants. INSET: This article at a glance.

  • The Effect of Bran on Bowel Function in Constipation. Graham, David Y.; Moser, Scott E.; Estes, Mary K. // American Journal of Gastroenterology;Sep1982, Vol. 77 Issue 9, p599 

    Bran is widely used to treat a variety of gastrointestinal disorders. With few exceptions, investigative work has focused on the effect of bran in normal subjects. Despite its widespread use, there have been no systematic studies of bran in constipation. Wheat bran is the "gold standard''...

  • Bowel Habit Reference Values and Abnormalities in Young Iranian Healthy Adults. Peyman Adibi; Ebrahim Behzad; Shahryar Pirzadeh; Masood Mohseni // Digestive Diseases & Sciences;Aug2007, Vol. 52 Issue 8, p1810 

    Abstract  The purpose of this study was to estimate the prevalence of self-reported, ROME II–defined constipation and determine the average defecation frequency and stool types in the Iranian population. A self-reported questionnaire was distributed to 1045...

  • Psychological Evaluation of Patients with Severe Idiopathic Constipation: Which Instrument to Use. Wald, Arnold; Bargio, Kathryn; Holeva, Karen; Locher, Julie // American Journal of Gastroenterology;Aug1992, Vol. 87 Issue 8, p977 

    We prospectively evaluated 38 patients with chronic severe idiopathic constipation who failed to respond to conventional therapy. Colonic transit studies, the Hopkins Symptom Checklist (SCL-90-R), and the Minnesota Multiphasic Personality Inventory (MMPI) were completed. Colonic transit studies...

  • Clinical: Red flag symptoms - Constipation. Singh, Pipin // GP: General Practitioner;6/24/2011, p41 

    The article presents information related to constipation. It has been stated that it is incomplete passage of hard stools that could be associated with straining, palpable faeces in the rectum and/or a sensation of incomplete defecation. It has been stated that poor intake of fibre and age could...

  • Dark secrets. Bates, Jane // Nursing Standard;7/18/2007, Vol. 21 Issue 45, p25 

    The article discusses the constipation problem in Hampshire, England. The cause of the problem is associated of the town's geology wherein the chalk substratum of the town permeates the water supply, destroys kitchen appliances and seals the pipes. To solve the problem, Hampshire should have tax...

  • Paroxetine.  // Reactions Weekly;5/21/2005, Issue 1052, p16 

    Examines constipation and xerostomia in an elderly patient. Complications of administering paroxetine.

  • RED FLAG SYMPTOMS Constipation. Croton, Lizzie // GP: General Practitioner;2/20/2009, p41 

    The article discusses the symptoms of constipation. Constipation is an extremely common problem seen by most general practitioners (GP). In determining its symptoms, a drug history is important, including both prescribed and over-the-counter (OTC) medications. It is important that patients...


Read the Article


Sign out of this library

Other Topics