Drug interactions with warfarin: what clinicians need to know

Juurlink, David N.
August 2007
CMAJ: Canadian Medical Association Journal;8/14/2007, Vol. 177 Issue 4, p369
Academic Journal
The article focuses on the complications related to drug interactions with warfarin and discusses several useful tips that clinicians should keep in mind for their effective treatment. It is stated that majority of drug interactions result in an increased risk of hemorrhage and many of them are also accompanied by elevated international normalized ratio. It is reported that effects of common participants of drug interactions with warfarin are mostly intuitive. Information is given about the mechanism of drug interactions with warfarin and the classes to which the interacting drugs belong. A chart depicting the drugs that interact with warfarin along with their mechanism of interaction and the associated risk of hemorrhage is also given.


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