Acquired hemophilia A presenting post partum

Mytopher, Kristine; Dudebout, Jill; Card, Robert; Gilliland, Barry
August 2007
CMAJ: Canadian Medical Association Journal;8/14/2007, Vol. 177 Issue 4, p339
Academic Journal
The article discusses several important diagnostic techniques for differential diagnosis of postpartum hemorrhage. It is stated that factor VIII inhibition may result in life-threatening hemorrhage in healthy young women, if not diagnosed. It is viewed that transplacental transfer of inhibitors may occur in women patients, and they must be counseled about this risk. It is reported that inhibitors disappear spontaneously after about 30 months and normally do not recur with subsequent pregnancies in most cases. Case study of the treatment of postpartum hemorrhage of a 41-year-old woman who presented herself in labor to the authors after 39 weeks of gestation with quiescent myasthenia is also given.


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