TITLE

Aquaporins with selectivity for unconventional permeants

AUTHOR(S)
Wu, B.; Beitz, E.
PUB. DATE
September 2007
SOURCE
Cellular & Molecular Life Sciences;Sep2007, Vol. 64 Issue 18, p2413
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The aquaporin protein family generally seems to be designed for the selective passage of water or glycerol. Charged molecules, metal ions and even protons are strictly excluded. Recently, particular aquaporin isoforms were reported to conduct unconventional permeants, i.e., the unpolar gases carbon dioxide and nitric oxide, the polar gas ammonia, the oxidative oxygen species hydrogen peroxide, and the metalloids antimonite, arsenite and silicic acid. Here, we summarize the available data on permeability properties and physiological settings of these aquaporins and we analyze which structural features might be connected to permeability for non-water, non-glycerol solutes.
ACCESSION #
26530278

 

Related Articles

  • Modelling carbon dioxide molecule interacting with aquaglyceroporin and aquaporin-1 channels. Al Garalleh, Hakim; Thamwattana, Ngamta; Cox, Barry; Hill, James // Journal of Mathematical Chemistry;Oct2013, Vol. 51 Issue 9, p2317 

    Aquaporin (AQP) is a family of membrane proteins that enable water and small individual molecules to permeate cell membranes. Examples of these protein channels are aquaglyceroporin and aquaporin-1 (AQP1). Here, we investigate the permeability of carbon dioxide $$(\hbox {CO}_2)$$ through both...

  • CO2 Transport by PIP2 Aquaporins of Barley. Mori, Izumi C.; Rhee, Jiye; Shibasaka, Mineo; Sasano, Shizuka; Kaneko, Toshiyuki; Horie, Tomoaki; Katsuhara, Maki // Plant & Cell Physiology;Feb2014, Vol. 55 Issue 2, p251 

    CO2 permeability of plasma membrane intrinsic protein 2 (PIP2) aquaporins of Hordeum vulgare L. was investigated. Five PIP2 members were heterologously expressed in Xenopus laevis oocytes. CO2 permeability was determined by decrease of cytosolic pH in CO2-enriched buffer using a hydrogen...

  • Physiological relevance of aquaporins: luxury or necessity? van Os, Carel H.; Kamsteeg, Erik-Jan; Marr, Nannette; Deen, Peter M.T. // Pflugers Archiv European Journal of Physiology;Aug2000, Vol. 440 Issue 4, p513 

    Aquaporins are members of a large family of pore-forming intrinsic membrane proteins, the MIP family. Based on their permeability properties they are now further subdivided into aquaporins, with real water-selective pores, and aquaglyceroporins with slightly less selective pores. Aquaporins are...

  • Stimulation of aquaporin-5 and transepithelial water permeability in human airway epithelium by hyperosmotic stress. Pedersen, Peter; Braunstein, Thomas; Jørgensen, Anders; Larsen, Per; Holstein-Rathlou, Niels-Henrik; Frederiksen, Ole // Pflugers Archiv European Journal of Physiology;Mar2007, Vol. 453 Issue 6, p777 

    Osmotic water permeability ( P f ) was measured in spheroid-shaped human nasal airway epithelial explants pre-exposed to increasing levels of hyperosmotic stress. The fluid-filled spheroids, derived from nasal polyps, were lined by a single cell layer with the ciliated apical cell membrane...

  • Aquaporinology. Benga, Gh. // Acta Endocrinologica (1841-0987);2014, Vol. 10 Issue 1, p1 

    The water channels milestones include: the vague idea of "hydrophilic pores" or "water-filled channels" in the red blood cell (RBC), the proposal that water channels (WCh) are accommodated in proteins, experiments associating WCh with the major RBC membrane protein called Band 3 (the anion...

  • Inhibition of CO2 production from glucose by arginine in brain slices of rats. Débora Delwing; Francieli Stefanello; Marcos Perry; Angela Wyse // Metabolic Brain Disease;Jun2007, Vol. 22 Issue 2, p145 

    Abstract  In the present study we evaluated the in vivo effect of arginine on CO2 production from glucose in a medium with physiological and high extracellular K concentrations. We also tested the influence of the nitric oxide synthase inhibitor, Nω-nitro-L-arginine...

  • Verification of the vibrational exciton approach for CO[sub 2] and N[sub 2]O nanoparticles. Signorell, Ruth // Journal of Chemical Physics;2/8/2003, Vol. 118 Issue 6, p2707 

    It is investigated how far the vibrational exciton approximation is suitable to describe the characteristic band shapes in the infrared spectra of CO[sub 2] and N[sub 2]O nanoparticles. The particles typically contain between 50 and 10[sup 4] molecules and have spatial dimensions between 1 and...

  • Stomatal conductance changes due to increasing carbon dioxide levels: Projected impact on surface ozone levels. Sanderson, M. G.; Collins, W. J.; Hemming, D. L.; Betts, R. A. // Tellus: Series B;Jul2007, Vol. 59 Issue 3, p404 

    The impact of increasing levels of carbon dioxide on stomatal conductance and surface ozone levels was investigated using a global three-dimensional general circulation model (GCM) coupled to an interactive land surface scheme and a chemistry model. Pre-industrial, present day and doubled...

  • Interpretation of excited state Hartree–Fock analytic derivative anomalies for NO2 and HCO2 using the molecular orbital Hessian. Burton, Neil A.; Yamaguchi, Yukio; Alberts, Ian L.; Schaefer, Henry F. // Journal of Chemical Physics;11/15/1991, Vol. 95 Issue 10, p7466 

    A simple procedure utilizing the molecular orbital (MO) Hessian, the second derivative of the Hartree–Fock (HF) energy with respect to MO coefficient perturbations, has been proposed in the interpretation of anomalous analytic HF energy derivatives. The nature of the anomalous analytic...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics