Survival after treatment for hyperammonaemic crises of urea cycle disorders

September 2007
Archives of Disease in Childhood;Sep2007, Vol. 92 Issue 9, p766
Academic Journal
The article focuses on the survival of patients after treatment for hyperammonaemic crises of urea cycle disorders. Low-protein diet, adequate calorie intake, alternative-pathway treatment for hyperammonaemic crises, and dialysis are some of the ways in treating urea cycle disorders. On the other hand, some scientists introduced the alternative-pathway treatment including the provision of phenylacetate and benzoate so that waste nitrogen is excreted as phenylacetylglutamine and N-benzoylglycine rather than producing ammonia. Detailed information about the results of the study of the new alternative ways is elaborated.


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