Tescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expression
- V-myc in a simple, single gene retroviral vector causes rapid induction of leukemia and concomitant apoptosis following bone marrow transplantation. Dolnikov, A; Shounan, Y; Millington, M; Mackenzie, K; Symonds, G // Leukemia (08876924);Apr98, Vol. 12 Issue 4, p542
We have previously developed an in vivo model of leukemogen-esis utilizing mice reconstituted with genetically modified bone marrow cells. Based on those studies, a new single gene retro-viral vector has been engineered which efficiently transfers v-myc into immature murine bone marrow cells....
- Bone marrow cells migrate to tumors and can slow their growth. // Biomedical Market Newsletter;10/10/2011, Vol. 21, p153
The article focuses on the study which examines the role of bone marrow-derived cells (BMDCs) on tumor growth, which shows that more effective treatment for cancer can be developed through exploitation of BMDCs, with bone marrow cells migrate and slow the growth of tumors.
- TROP2 expression and its correlation with tumor proliferation and angiogenesis in human gliomas. Ning, Shanglei; Liang, Nan; Liu, Bin; Chen, Xin; Pang, Qi; Xin, Tao // Neurological Sciences;Oct2013, Vol. 34 Issue 10, p1745
Trophoblast cell surface antigen 2 (TROP2) is a transmembrane glycoprotein which is associated with tumor development and progression in a variety of epithelial carcinomas, while its expression and role in gliomas have not been considered. The aim of the study was to investigate TROP2 expression...
- Correlation of cyclin D1 transcript levels, transcript type and protein expression with proliferation and histology among mantle cell lymphoma. Shakir, R.; Ngo, N.; Naresh, K. N. // Journal of Clinical Pathology;Aug2008, Vol. 61 Issue 8, p920
Background: Cyclin D1 expression is central to mantle cell lymphoma (MCL) biology. The cyclin D1 gene produces two forms of mRNA: long (D1L) and short (D1S) versions. Aims: To study the relationship between histology, cyclin D1 mRNA (transcript) levels, cyclin D1 transcript type, cyclin D1...
- Antitumor effect of Interferon-beta cDNA engineered human bone marrow mesenchymal stem cells to prostate cancer in vitro. Gongxian Wang; Yian Zhan; Yang Wang; HongLin Hu; Haiming Sang // Cell Research;Aug2008 Supplement, Vol. 18, pS65
Our purpose is to investigate the effect of human interferon-beta (huIFN-Î²) gene cDNA engineered human bone marrow mesenchymal stem cells (hMSCs) inhibit the growth of prostate cancer cell line PC-3 (PC-3) in vitro, and investigate a therapeutic strategy about the local production of...
- Signaling Between Tumor Cells and the Host Bone Marrow Microenvironment. Kovacic, Natasa; Croucher, Peter; McDonald, Michelle // Calcified Tissue International;Jan2014, Vol. 94 Issue 1, p125
Tumor cells with high skeletal homing affinity express numerous cell surface receptors that bind ligands produced in bone. Upon arrival, these cells survive in the host environment, encompassed in close proximity to bone marrow cells. Interactions between tumor cells and cells of the host...
- Radiation Oncology Centers (ROC). // Sarasota Magazine;Oct2001, Vol. 24 Issue 1, p204
Focuses on some oncology centers based on Sarasota, Florida. Significance of individual attention; Way in which growth of cancerous cells are checked; Emphasis laid on the use of advanced technology.
- Use of 5-[76Br]bromo-2'-fluoro-2'-deoxyuridine as a ligand for tumour proliferation: validation in an animal tumour model. Borbath, Ivan; Gr�goire, Vincent; Bergstr�m, Mats; Laryea, Daniel; L�ngstr�m, Bengt; Pauwels, Stanislas // European Journal of Nuclear Medicine & Molecular Imaging;2002, Vol. 29 Issue 1, p19
Uncontrolled cell proliferation is one of the prominent features in cancer development. Precise tools are needed for determination of the proliferation rate before, during and after treatment, thereby permitting assessment of treatment efficacy. The purpose of this study was to validate the...
- Erratum to: Effect of the modulation of leucine zipper tumor suppressor 2 expression on proliferation of various cancer cells functions as a tumor suppressor. Kim, Jong; Song, Ji; Cho, Hyun; Shin, Keun; Bae, Yong; Lee, Byung; Jung, Jin // Molecular & Cellular Biochemistry;Feb2012, Vol. 361 Issue 1/2, p345
A correction to the article "Effect of the modulation of leucine zipper tumor suppressor 2 expression on proliferation of various cancer cells functions as tumor suppressor," that was published in the December 6, 2011 is presented.