TITLE

Stress-related changes in oesophageal permeability: filling the gaps of GORD?

AUTHOR(S)
Söderholm, Johan D.
PUB. DATE
September 2007
SOURCE
Gut;Sep2007, Vol. 56 Issue 9, p1177
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Albeit remaining a controversial issue, it has become increasingly recognised that psychological stress has a major impact on gut mucosal function and affects the course of gastrointestinal disorders. Research during the last decade has shown that stress causes barrier dysfunction of the gastrointestinal mucosa by mechanisms that mainly involve neuropeptides and mast cells. Moreover, accumulating evidence implicates increased permeability as a pathogenic factor in gastroesophageal reflux disease (GORD). Recent data demonstrating that psychological stress may induce a permeability defect in stratified epithelia, including the oesophagus, shed new light on the pathophysiological events leading to heartburn and GORD.
ACCESSION #
26437218

 

Related Articles

  • Quality of life assessment in gastro-oesophageal reflux disease. Irvine, E. J. // Gut;May2004 Supplement 4, Vol. 53, piv35 

    Health related quality of life (HRQoL) is determined by both disease and non-disease related factors. Several studies have reported significant HRQOL impairment in GORD patients compared with the general population. Disease severity correlates strongly with HRQoL. Non-disease features, such as...

  • GERD BEYOND THE ESOPHAGUS. Magill-Lewis, Jillene // Drug Topics;4/15/2002, Vol. 146 Issue 8, p62 

    Provides information on the gastroesophageal reflux disease. Symptoms; Developments in drugs for treatment of the disease; Role of pharmacists in the treatment of the disease.

  • hard to swallow. Drury, Kathryn // Vegetarian Times;Apr2001, Issue 284, p68 

    Focuses on gastroesophageal reflux disease (GERD), a condition characterized by frequent occurrence of heartburn. Pathophysiology; Causes; Foods that can help relieve the pain; Role of stress in increasing risks for GERD.

  • Reducing stress won't quench those fiery heartburn pains. Letsche, Amber Lee // Fort Worth Business Press;6/22/2001, Vol. 14 Issue 8, p18 

    Corrects misconceptions that stress causes heartburn. Heartburn as a symptom of gastroesophageal reflux disease (GERD); Causes of GERD; Ways in which stress can aggravate heartburn.

  • Ambulatory Esophageal pH Recording in Gastroesophageal Reflux: Relevance to the Development of Esophagitis. Rokkas, T.; Sladen, G. E. // American Journal of Gastroenterology;Jun1988, Vol. 83 Issue 6, p629 

    In a group of 60 patients with symptomatic gastroesophageal reflux (GER), we carried out upper gastrointestinal (GI) endoscopy and 24-h ambulatory esophageal pH monitoring to assess the relationship between acid reflux and esophagitis. The results of 24-h pH measurement were compared with those...

  • Gastroesophageal Reflux in Children: When to be Concerned. Chitkara, Denesh; Martin, Nannette; Kelly, Maureen // Pediatrics for Parents;2006, Vol. 22 Issue 8, p7 

    The article talks about gastroesophageal reflux, the passage of stomach contents into the esophagus, which is a common problem in infants and children that typically occurs during or after a meal in 50 percent of newborns and up 67 percent of four month-old infants. The frequent episodes of...

  • pH-impedance monitoring value in diagnosis of gastroesophageal reflux in children and teenagers - preliminary report. Szaflarska-Popławska, Anna; Mierzwa, Grażyna; Bała, Grażyna; Parzȩcka, Monika; Kuczyńska, Renata // Gastroenterologia Polska / Gastroenterology;2007, Vol. 14 Issue 4, p251 

    Aim of study: The aim of the study was assessment concerning pH-impedance usefulness in diagnostics of gastroesophageal reflux (GER) in children and teenagers. Material and methods: 53 children and teenagers were included into the study, aged from 7 to 18 years (the average age - 15 years),...

  • Whither surgery in the treatment of gastroesophageal reflux disease (GERD)?  // CMAJ: Canadian Medical Association Journal;1/20/2004, Vol. 170 Issue 2, p219 

    Provides information on gastroesophageal reflux disease (GERD), a risk factor for esophageal cancer. Drugs that are highly effective in the treatment of GERD; Example of surgical antireflux procedure for GERD; Important trends in therapeutic approaches to GERD.

  • Impact of gastroesophageal reflux disease on daily life: the Systematic Investigation of Gastrointestinal Diseases in China (SILC) epidemiological study. Rui Wang; Duowu Zou; Xiuqiang Ma; Zhao, Yanfang; Xiaoyan Yan; Hong Yan; Jiqian Fang; Ping Yin; Xiaoping Kang; Qiang Li; Dent, John; Sung, Joseph J.; Halling, Katarina; Johansson, Saga; Wenbin Liu; Jia He // Health & Quality of Life Outcomes;2010, Vol. 8, p128 

    Background: Gastroesophageal reflux disease imposes a significant burden of illness in Western populations. However, data on the impact of reflux symptoms on daily life in Asian populations are scarce. The current study aimed to evaluate the impact of GERD (defined on the basis of symptoms) on...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics