TITLE

Experience-dependent recovery of vision following chronic deprivation amblyopia

AUTHOR(S)
Hai-Yan He; Ray, Baisali; Dennis, Katie; Quinlan, Elizabeth M.
PUB. DATE
September 2007
SOURCE
Nature Neuroscience;Sep2007, Vol. 10 Issue 9, p1134
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The shift in ocular dominance induced by brief monocular deprivation is greatest during a postnatal critical period and is thought to decline irreversibly thereafter. However, here we demonstrate that complete visual deprivation through dark exposure restores rapid ocular dominance plasticity in adult rats. In addition, the loss of visual acuity resulting from chronic monocular deprivation is reversed if dark exposure precedes removal of the occlusion in adulthood, suggesting a potential use for dark exposure in the treatment of adult amblyopia.
ACCESSION #
26358279

 

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