Clinicopathologic correlations in eyes enucleated after uveal melanoma resection with positive surgical margins

Khalifa, Yousuf; Aaberg Jr., Thomas M.; Aaberg Sr., Thomas M.; Grossniklaus, Hans E.; Aaberg, Thomas M Jr; Aaberg, Thomas M Sr
September 2007
Indian Journal of Ophthalmology;Sep2007, Vol. 55 Issue 5, p380
Academic Journal
journal article
We identified three eyes that had undergone enucleation after transscleral resection of uveal melanoma. Two enucleated eyes with microscopically positive margins of resection exhibited no evidence of residual melanoma and these patients were alive without metastasis with at least four years' follow-up. One eye with a transected melanoma contained residual melanoma and that patient died with metastatic melanoma to the liver three years after enucleation. There appear to be at least two general types of positive surgical margins of resection of uveal melanoma: microscopically positive margins and macroscopically positive (transected) margins of resection.


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