TITLE

Prevalence of Human Herpes Virus-8 and Hepatitis B Virus among HIV Seropositive Pregnant Women Enrolled in the Mother-to-child HIV Transmission Prevention Program at Saint Camille Medical Centre in Burkina Faso

AUTHOR(S)
Ilboudo, Denise; Karou, Damintoti; Nadembega, Wendyame M. C.; Savadogo, Aly; Djeneba, Ouermi; Pignatelli, Salvatore; Pietra, Virginio; Bere, Augustin; Simpore, Jacques; Traore, Alfred S.
PUB. DATE
September 2007
SOURCE
Pakistan Journal of Biological Sciences;2007, Vol. 10 Issue 17, p2831
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The aims of this research are: i) to evaluate the prevalence of HHV-8, HBV and HIV among pregnant women, ii) to determine the percentage of these co-infections and iii) to estimate the frequency of the mother-to-child transmission of HIV among HBV and HHV-8 positive mothers. Thus, 379 pregnant women attending ante-natal consultation in Saint Camille Medical Centre were subject to HIV, HHV-8 antibodies and the viral marker Hepatitis B Surface Antigen (HBsAg) detection. We observed 48/379 (12.66%) HIV seropositive subjects. Among them, HIV-1 type infection was predominant (95.83%), only 2/48 (4.17%) subjects had a dual HIV-1 type and HIV-2 type infection, no single HIV-2 type infection was detected. 38/379 (10.02%) subjects were infected by HHV-8 and 30/379 (7.91%) were HBsAg positive, HHV-8 and HIV Co-infections rates were high within HBV positive patients and we had respectively 20.00 and 16.67%. 10.42% HIV positive women were co-infected by HBV while 12.50% were infected by HHV-8. Then, 15.79% subjects HHV-8 positive were co-infected by HBV or HIV. In spite of the PMTCT protocol application, five (10.42%) HIV positive women transmitted the virus to their children. Two HIV positive mothers were co-infected by HHV-8 and one by HBV. Among the 5 HIV infected, one mother (20.0%) was HBV positive and two (40.0%) HHV-8 positive. Although we did not have a large sample which would show large prélalences of the infections, we could put forward that the Co-infection of the HIV with one of these viruses (HBV or HHV-8) could favorite the mother-to-child transmission.
ACCESSION #
26200707

 

Related Articles

  • Co-Infection of Toxoplasma gondii with HBV in HIV-Infected and Uninfected Pregnant Women in Burkina Faso. Ouermi, D.; Simpore, J.; Belem, A. M. G.; Sanou, D. S.; Karou, D. S.; Ilboudo, D.; Bisseye, C.; Canadja, S. M.; Pietra, V.; Pignatelli, S.; Gnoula, C.; Nikiema, J. B.; Kabre, G. B. // Pakistan Journal of Biological Sciences;2009, Vol. 12 Issue 17, p1188 

    Toxoplasma gondii infectious can induce serious complications in HIV-infected pregnant women, leading to miscarriage; favour the mother-to-child transmission of HBV and HIV and birth defects. The purposes of this study were: (1) to quantify IgM and IgG antibodies to Toxoplasrna gondii in...

  • Reducing direct causes of maternal death. Pattinson, R. C. // South African Journal of Obstetrics & Gynaecology;Sep2013, Vol. 19 Issue 3, p59 

    The article reports on the launch of a massive campaign to lessen deaths because of complications of HIV infection. It mentions that all pregnant women who are infected with HIV go onto a single-tablet antiretroviral therapy and pregnant women have been introduced on antiretroviral therapy at...

  • What is drug safety?: celebrating 20 years of the Drug Safety journal. Edwards, I. Ralph // Drug Safety;2006, Vol. 29 Issue 6, p461 

    The expanded use of multiple antiretroviral drugs during pregnancy has led to a reduction in the occurrence of perinatal transmission of HIV to <2%, but has led to concerns regarding both short-term toxicity and the long-term impact on the woman and her child. Enhanced toxicity of nevirapine...

  • Treating HIV during pregnancy: an update on safety issues. Watts, D. Heather // Drug Safety;2006, Vol. 29 Issue 6, p467 

    The expanded use of multiple antiretroviral drugs during pregnancy has led to a reduction in the occurrence of perinatal transmission of HIV to <2%, but has led to concerns regarding both short-term toxicity and the long-term impact on the woman and her child. Enhanced toxicity of nevirapine...

  • Effects of Valacyclovir on Markers of Disease Progression in Postpartum Women Co-Infected with HIV-1 and Herpes Simplex Virus-2. Roxby, Alison C.; Drake, Alison L.; Ongecha-Owuor, Francisca; Kiarie, James N.; Richardson, Barbra; Matemo, Daniel N.; Overbaugh, Julie; Emery, Sandra; John-Stewart, Grace C.; Wald, Anna; Farquhar, Carey // PLoS ONE;Jun2012, Vol. 7 Issue 6, p1 

    Objective: Herpes simplex virus type 2 (HSV-2) suppression has been shown to reduce HIV-1 disease progression in nonpregnant women and men, but effects on pregnant and postpartum women have not been described. Methods: We analyzed data from a cohort of Kenyan women participating in a randomized...

  • From the Editor. Myer, Landon // Southern African Journal of HIV Medicine;Nov2012, Vol. 13 Issue 4, p158 

    The article discusses various reports published within the issue including one by C. E. Martin and colleague on the role of isoniazid preventive therapy (IPT) for tuberculosis in HIV infected pregnant women and another by D. Besada and colleagues on ART for all HIV-infected pregnant women.

  • Genotypic resistance testing in HIV-infected pregnant women in an urban setting. Shah, S.S.; Crane, M.; Monaghan, K.; McGowan, J.P. // International Journal of STD & AIDS;Aug2004, Vol. 15 Issue 8, p567 

    A correction to the article "Genotypic resistance testing in HIV-infected pregnant women in an urban setting" that was published in the 2004 issue of the International Journal of STD & AIDS is presented.

  • Risk factors for HCV infection in HIV positive pregnant women and rate of HCV perinatal transmission in Thailand. Ngo-Giang-Huong, Nicole; Decker, Luc; Sirirungsi, Wasna; Le Coeur, Sophie; Jourdain, Gonzague; Khamduang, Woottichai; Kanjanavanit, Suparat; Matanasaravoot, Wanmanee; Putiyanun, Chaiwat; Barin, Francis; Lallemant, Marc // Retrovirology;2009 Supplement 1, Vol. 6, p1 

    An abstract of the article "Risk factors for HCV infection in HIV positive pregnant women and rate of HCV perinatal transmission in Thailand," by Nicole Ngo-Giang-Huong and colleagues, is presented.

  • Increased exposure to hepatitis B virus infection in HIV-positive South African antenatal women. Burnett, R J; Ngobeni, J M; François, G; Hoosen, A A; Leroux-Roels, G; Meheus, A; Mphahlele, M J // International Journal of STD & AIDS;Mar2007, Vol. 18 Issue 3, p152 

    The prevalence of markers for hepatitis B virus (HBV) exposure and active infection in HIV-positive (n = 710) and HIV-negative (n= 710) pregnant South African women was investigated. The following statistically significant increases in the HIV-positive group were found: anti-hepatitis B core...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics