TITLE

Isolation and Characterization of Flavanone Glycoside 4I, 5, 7-Trihydroxy Flavanone Rhamnoglucose from Garcinia kola Seed

AUTHOR(S)
Okwu, D. E.; Morah, F. N. I.
PUB. DATE
January 2007
SOURCE
Journal of Applied Sciences;2007, Vol. 7 Issue 2, p306
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The ethanolic extract of Garcinia kola, Heckel (Guttiferae), which had previously been shown to have biological activity were studied. Preliminary phytochemical screening of the plants showed the presence of flavonoids, phenolic compounds, tannins and saponins. The ethanolic extract of Garcinia kola seeds resulted in the isolation and characterization of flavanone glycoside 4', 5, 7-trihydroxyflavonone rhamnoglucose (that is naringin-7-rharmnoglucoseside) from its spectral data. 1HNMR spin system analysis and acid hydrolysis were performed to characterize the higher order rhamnoglucosyl moiety comprising glucose and rhamnose linked to carbon 7 of the flavanone ring system of the isolate. It is concluded that 4', 5, 7-trihydroxyflavanone rhamnoglucose may be a contributor to the antioxidants, anti-inflammatory, anti-microbial, anti-rumor and anti-hepatotoxic properties exhibited by Garcinia kola seed.
ACCESSION #
26019709

 

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