Review: Evidence from observational studies, but not randomized trials, suggests that long-term aspirin prevents colorectal cancer
- Low-dose aspirin plus endoscopy cost effective for CRC prevention. // PharmacoEconomics & Outcomes News;11/26/2011, Issue 642, p14
The article discusses a study which examined the lifetime cost effectiveness of prevention strategies for colorectal cancer (CRC) including aspirin, sigmoidoscopy, sigmoidoscopy plus aspirin, colonoscopy and colonoscopy plus aspirin.
- Review: NSAIDS and COX-2 inhibitors may prevent colorectal cancer but increase gastrointestinal and cardiovascular harm. // ACP Journal Club;Jul/Aug2007, Vol. 147 Issue 1, p16
The article cites a study, conducted by A. Rostom and colleagues, which focuses on the effectiveness of nonsteroidal antiinflammatory drugs (NSAIDs) and cyclooxygenase-2 (COX-2) inhibitors in primary prevention of colorectal cancer. The researchers employed English language studies to evaluate...
- The 45+ pill. // India Today;1/31/2011, p45
The article reports on the British Royal Society of Medicine's suggestions to take aspirin daily at age 45, based on the findings by Oxford University researchers that show that daily intake of 75 milligram of aspirin for five years can reduce the risk of bowel cancer by a fourth.
- Low-dose aspirin taken long term reduced incidence of, mortality from colorectal cancer. // Hem/Onc Today;11/25/2010, Vol. 11 Issue 22, p60
The article focuses on a study which showed that the incidence of colorectal cancer can be reduced by about one-quarter and mortality from the disease by more than one-third with long-term use of aspirin taken at doses of at least 75 milligrams, held by researchers from the University of Oxford...
- Clinical digest. Long-term aspirin use found to reduce hereditary colorectal cancer development. // Nursing Standard;1/25/2012, Vol. 26 Issue 21, p16
The article discusses research which was reported in the article "Long-Term Effect of Aspirin on Cancer Risk in Carriers of Hereditary Colorectal Cancer: An Analysis From the CAPP2 Randomised Controlled Trial" by J. Burn et al., which found that the long term use of aspirin can reduce the...
- Colorectal Adenocarcinoma Spread Through Small Vessels. Puppa, Giacomo; Colombari, Romano; Chilosi, Marco; Pelosi, Giuseppe // International Journal of Surgical Pathology;Oct2008, Vol. 16 Issue 4, p438
The article cites a study on colorectal cancer spread through small vessels of the organs concerned. According to researchers, in such tumors, vascular invasion by neoplastic cells are considered to be a strong adverse prognostic factor. Tumors are caused by the overexpression of fascin,...
- Response to Neis et al. Ford, Alexander C; Talley, Nicholas J // American Journal of Gastroenterology;Dec2013, Vol. 108 Issue 12, p1930
A response from the authors of the article "Association between constipation and colorectal cancer: systematic review and meta-analysis of observational studies" in a previous issue of 2013.
- Journal Watch. // Pulse;4/26/2007, Vol. 67 Issue 16, p17
The article presents several medical research published in various journals. A Swedish study published in "Stroke" has found that stroke patients have a risk of acquiring depression. The "Journal of the National Cancer Institute" has published the results of the Cancer Prevention Study, which...
- Global gene expression analysis in time series following N-acetyl L-cysteine induced epithelial differentiation of human normal and cancer cells in vitro. Gustafsson, Anna C.; Kupershmidt, Ilya; Edlundh-Rose, Esther; Greco, Giulia; Serafino, Annalucia; Krasnowska, Eva K.; Lundeberg, Thomas; Bracci-Laudiero, Luisa; Romano, Maria-Concetta; Parasassi, Tiziana; Lundeberg, Joakim // BMC Cancer;2005, Vol. 5, p1
Background: Cancer prevention trials using different types of antioxidant supplements have been carried out at several occasions and one of the investigated compounds has been the antioxidant N-acetyl-L-cysteine (NAC). Studies at the cellular level have previously demonstrated that a single...