Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in human bone

Shead, Elizabeth F.; Haworth, Charles S.; Condliffe, Alison M.; McKeon, Damian J.; Scott, Mike A.; Compston, Juliet E.
July 2007
Thorax;Jul2007, Vol. 62 Issue 7, p650
Academic Journal
The article presents information related to expression of cystic fibrosis transmembrane conductance regulator (CFTR) in bone cells. An immunolocalisation of CFTR in human neonatal bone section showed the presence of CFTR expression in osteocytes newly incorporated into bone, whereas more deeply embedded osteocytes showed no CFTR expression. The researcher concluded that expression of CFTR in bone cells might have a physiological role.


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