TITLE

Challenges in pulmonary fibrosis · 2 : Bronchiolocentric fibrosis

AUTHOR(S)
Cordier, Jean-François
PUB. DATE
July 2007
SOURCE
Thorax;Jul2007, Vol. 62 Issue 7, p638
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Bronchiolocentric fibrosis is essentially represented by the pathological pattern of constrictive fibrosis bronchiolitis obliterans. The corresponding clinical condition (obliterative bronchiolitis) is characterised by dyspnoea, airflow obstruction at lung function testing and air trapping with characteristic mosaic features on expiratory high resolution CT scans. Bronchiolitis obliterans may result from many causes including acute diffuse bronchiolar damage after inhalation of toxic gases or fumes, alloimmune chronic processes after lung or haematopoietic stem cell transplantation, or connective tissue disease (especially rheumatoid arthritis). Airway-centred interstitial fibrosis and bronchiolar metaplasia are other features of bronchiolocentric fibrosis.
ACCESSION #
25757877

 

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