Effects of Apoptosis and ROS Production on Fertilization and Blastocyst Development

July 2007
Fertility Weekly;7/9/2007, p10
Academic Journal
The article relates a study that determines the impact of granulosa cell apoptosis and reactive oxygen species (ROS) production on oocyte fertilization, embryo development, and implantation rate. The study of N. Jancar and colleagues on 30 normally cycling women who were undergoing in vitro fertilization-embryo transfer due to tubal factor infertility shows that ROS species production and apoptosis in granulosa cells do not significantly affect oocyte fertilization and blastocyst development.


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