TITLE

Sensitive bioanalysis—combining single-molecule spectroscopy with mono-labeled self-quenching probes

AUTHOR(S)
Marmé, Nicole; Knemeyer, Jens-Peter
PUB. DATE
July 2007
SOURCE
Analytical & Bioanalytical Chemistry;Jul2007, Vol. 388 Issue 5/6, p1075
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Fluorescence single-molecule spectroscopy is an appropriate tool for modern bioanalysis. This technique enables the development of ultra sensitive assays, especially when combined with self-quenching probes. In this review we report novel DNA, enzyme, and antibody assays based on mono-labeled fluorescent probes that are quenched by photoinduced electron transfer (PET).
ACCESSION #
25603350

 

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