TITLE

Pancreatic protease-activated receptors: friend and foe

AUTHOR(S)
Gorelick, Fred
PUB. DATE
July 2007
SOURCE
Gut;Jul2007, Vol. 56 Issue 7, p901
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article comments on a paper which examines the effects of protease-activated receptor 2 (PAR2) activation on the inhibited secretion found in acute pancreatitis. The author stresses that this study confirms that deletion of PAR2 worsens pancreatitis responses in the caerulein model. He emphasizes that the paper raises some interesting mechanistic questions. He asserts the implication of the study on translating the protective effect of PAR2 activation into treatment.
ACCESSION #
25602392

 

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