Helicobacter bills: bacterial provocateur orchestrates host immune responses to commensal flora in a model of inflammatory bowel disease

Fox, J. G.
July 2007
Gut;Jul2007, Vol. 56 Issue 7, p892
Academic Journal
The article comments on a paper which uses Helicobacter bilis bacteria to elicit inflammatory bowel disease model in commensal altered Schaedler flora (ASF). The author stresses that the model of IBD is intriguing and very useful. He emphasizes that H bilis-infected mice may have activated dendritic cells that are capable of processing luminal enteric bacterial antigens. He asserts that if the bacteria induces lower bowel inflammatory response to ASF antigens, one would expect chronic colitis.


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