Live viral vaccines in a DiGeorge syndrome patient

Waters, V.; Peterson, K. S.; LaRussa, P.
June 2007
Archives of Disease in Childhood;Jun2007, Vol. 92 Issue 6, p519
Academic Journal
We report a case of pneumonia in a 13 month old male child with partial DiGeorge syndrome who died after inadvertently receiving live viral vaccines. Although live viral vaccines have been used safely in some children with DiGeorge syndrome, there are insufficient data to recommend their routine use in those with severe immunodeficiency.


Related Articles

  • Reading the warning signs of primary immunodeficiency. Koleilat, Majed A.; Williams, Larry W.; Ryan, Michael E. // Contemporary Pediatrics;Jun2003, Vol. 20 Issue 6, p65 

    Provides information on characteristics of primary immunodeficiency disorders to familiarize pediatricians and family physicians. Signs of primary immunodeficiency; Types of immunodeficiency disorders; Cases of children with primary immunodeficiency disorders. INSETS: Examples of major primary...

  • Successful Gene Therapy for Severe Combined Immunodeficiency. Rosen, Fred S. // New England Journal of Medicine;4/18/2002, Vol. 346 Issue 16, p1241 

    Editorial. Focuses on the incidence of severe combined immunodeficiency in children. Use of gene therapy in the treatment of immunodeficiency; Hereditary aspect of the disease; Risk factors for immunodeficiency; Mentions an article in this issue by Hacein-Bey-Abina.

  • Status of primary immunodeficiency disorders in India. Chopra, Yogi; Yadav, Satya // Indian Pediatrics;Oct2013, Vol. 50 Issue 10, p974 

    The authors discusses cases of primary immunodeficiency disorders (PID), highlighting the possibility of improved pan-India survival rate.

  • Newborn Testing for Immune Disorders Could Save Lives.  // Ascribe Newswire: Medicine;4/22/2004, p66 

    A simple, inexpensive blood test performed at birth to screen for immune disorders could dramatically increase the chance of survival for babies born with such potentially fatal disorders as severe combined immunodeficiency disease (SCID). Physicians at Duke University Medical Center have...

  • JALEA REAL; AN EFFECTIVE ALTERNATIVE FOR THE TREATMENT OF PATIENT WITH CELLULAR IMMUNODEFICIENCY. De la Guardia, O.; Espinosa, J.; Planos, T.; Savigne, M.; Nogueira, L.; Lemus, Z.; M. // Revista VacciMonitor (Vacunología y Temas Afines);Oct2002, Vol. 11 Issue 4, p1 

    Jalea Real is a nutritional supplement characterized by its great contribution of proteins, vitamins, minerals, amino acids and fatty acids. The knowledge of these properties has allowed that many investigators have reported that this nutritional supplement significantly increases hemoglobin...

  • Cellular Immunity Before and After Leptin Replacement Therapy. Paz-Filho, Gilberto Jorge; Delibasi, Tuncay; Erol, Halil Kutlu; Ma-Li Wong; Licinio, Julio // Journal of Pediatric Endocrinology & Metabolism;Nov2009, Vol. 22 Issue 11, p1069 

    The article focuses on an evaluation if there are any immune defects on a newly-identified leptin-deficient baby. The baby underwent several assessments before the initiation of recombinant methionyl human leptin, which includes an analysis of humoral immunity by measurement of several...

  • Treatment with cyclosporin A in a patient with Omenn's syndrome. Meyer-Bahlburg, A.; Haas, J.-P.; Haase, R.; Eschrich, U.; Wawer, A.; Frank, L.; Marsch, W.Ch. // Archives of Disease in Childhood;Sep2002, Vol. 87 Issue 3, p231 

    Reports a case study wherein an infant suffering from Omenn's syndrome was treated with cyclosporin A. Cyclosporin A treatment of the infant prior to hematopoietic stem cell transplantation; Use of immunosuppressive therapy to control activation of autoreactive T lymphocyte; Normalization of...

  • Humoralna imunost u djece sa imunodeficijencijama i imunosupresijom. Čolić-Hadžić, Belkisa; Mladina, Nada; Hadžić, Devleta // Medicinski Arhiv;2009, Vol. 63 Issue 1, p9 

    The objective of the study was to determine the immunological characteristics of immunodeficiency and immunosuppression in children and to estimate the type of disorder within the immunological system. In the prospective study with 90 patients included, all were separated into three groups (30...

  • Molecular defects in T- and B-cell primary immunodeficiency diseases. Cunningham-Rundles, Charlotte; Ponda, Prashant P. // Nature Reviews Immunology;Nov2005, Vol. 5 Issue 11, p880 

    More than 120 inherited primary immunodeficiency diseases have been discovered in the past five decades, and the precise genetic defect in many of these diseases has now been identified. Increasing understanding of these molecular defects has considerably influenced both basic and translational...


Read the Article

Other Topics