TITLE

Activation of the epithelial Na+ channel (ENaC) requires CFTR CI- channel function

AUTHOR(S)
Reddy; Light, M.M.
PUB. DATE
November 1999
SOURCE
Nature;11/18/1999, Vol. 402 Issue 6759, p301
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Examines the ion channel regulation in the genetic disease cystic fibrosis. Dependence of epithelial Na+ channel on CFTR activity; Primary defect in Cl- channel permeability in cystic fibrosis; Factors in the reduced salt absorption in cystic fibrosis.
ACCESSION #
2537965

 

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