Severity of obstructive apnoea in children with Down syndrome who snore

Fitzgerald, Dominic A.; Paul, Annette; Richmond, Clare
May 2007
Archives of Disease in Childhood;May2007, Vol. 92 Issue 5, p423
Academic Journal
Diagnostic overnight polysomnograms of 33 children with Down syndrome who snored were reviewed. Mean age was 4.9 years, none had had adenotonsillectomy, 91% were non-obese (Down syndrome specific body mass index standard deviation score (BMI SDS) <+2.0) and yet 97% demonstrated obstructive sleep apnoea, with an average apnoea hypopnoea index (AHI) of 12.9 episodes per hour (normal <1) and an average oxygen desaturation of 4%. A higher AHI was associated with lower minimum SpO2, higher TcCO2 and higher number of arousals from sleep per hour (p<0.001). Polysomnography should be a routine investigation for children with Down syndrome who snore regardless of body habitus.


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