Familial liver disease

Spiller, Robin
May 2007
Gut;May2007, Vol. 56 Issue 5, p676
Academic Journal
The article solicits responses regarding the diagnosis of a 52-year-old man who underwent malaise and abnormal liver function tests. According to the author, the patient had no medical history and had never consumed alcohol. Clinical examinations and viral markers for hepatitis were negative. Esophagogastroduodenoscopy revealed grade IV esophageal varices and a liver biopsy was then carried out.


Related Articles

  • CORRECTIONS.  // Annals of Internal Medicine;4/7/2009, Vol. 150 Issue 7, p504 

    Two corrections to the article "Clinical Implications of Short-Term Variability in Liver Function Test Results" and "In the Clinic: Alcohol Use," that was published in April 7, 2009 issue are presented.

  • Abdominal distension and upper extremity muscle wasting in a 59-year-old woman. Kinzel, Julie // JAAPA: Journal of the American Academy of Physician Assistants (;Jun2014, Vol. 27 Issue 6, p59 

    No abstract available.

  • Biomarkers of Liver Status in Heavy Drinkers, Moderate Drinkers and Abstainers. Alatalo, Päivikki; Koivisto, Heidi; Puukka, Katri; Hietala, Johanna; Anttila, Petra; Bloigu, Risto; Niemeläi,, Onni // Alcohol & Alcoholism;Mar/Apr2009, Vol. 44 Issue 2, p199 

    Aims: Although a wide variety of biomarkers reflecting liver status are known to be influenced by excessive ethanol consumption, the dose-response relationships between ethanol intake and marker changes have remained less understood. Methods: Serum gamma-glutamyltransferase (GGT), aspartate...

  • "Odd-looking" oesophageal varices. Wiechowska-Kozowska, A.; Biaek, A.; Wójcicki, M.; Milkiewicz, P. // Gut;Apr2009, Vol. 58 Issue 4, p519 

    The article presents a case study of a 62-year-old man having mild dysphagia and upper abdominal discomfort. It describes unusual looking oesophageal varices as he underwent upper gastrointestinal endoscopy and was referred to the center for further investigation of possible portal hypertension....

  • Nonalcoholic steatohepatitis: cirrhosis, hepatocellular carcinoma, and burnt-out NASH. Yoshioka, Yoko; Hashimoto, Etsuko; Yatsuji, Satoru; Kaneda, Hiroyuki; Taniai, Makiko; Tokushige, Katsutoshi; Shiratori, Keiko // Journal of Gastroenterology;2004, Vol. 39 Issue 12, p1215 

    Nonalcoholic steatohepatitis (NASH) is a liver disease characterized by the histological features of steatohepatitis in the absence of significant alcohol consumption. The natural history of NASH is poorly defined. Here we report our experience with a patient to illustrate the clinical course of...

  • Epidemiology and Genetic Epidemiology of the Liver Function Test Proteins. Rahmioglu, Nilufer; Andrew, Toby; Cherkas, Lynn; Surdulescu, Gabriela; Swaminathan, Ramasamyiyer; Spector, Tim; Ahmadi, Kourosh R. // PLoS ONE;2009, Vol. 4 Issue 2, p1 

    Background: The liver function test (LFT) is among the most commonly used clinical investigations to assess hepatic function, severity of liver diseases and the effect of therapies, as well as to detect drug-induced liver injury (DILI). Aims: To determine the relative contribution of genetic and...

  • Efficacy of Short-Term Interferon Therapy for Patients Infected with Hepatitis C Virus Genotype 2a. Tabaru, Akinari; Narita, Ryoichi; Hiura, Masaaki; Abe, Shintaro; Otsuki, Makoto // American Journal of Gastroenterology;Apr2005, Vol. 100 Issue 4, p862 

    BACKGROUND AND AIMS: The efficacy of interferon (IFN)-based antiviral therapy for chronic hepatitis C (CHC) varies depending on predictive factors such as hepatitis C virus (HCV) genotype and viral load. For patients with good predictive factors, a low dose and short course of IFN-based therapy...

  • No need for LFTs with statin. Praities, Nigel // Pulse;4/8/2009, Vol. 69 Issue 12, p3 

    The article reports on the findings of the study by British researchers regarding the association between simvastatin intake and development of hepatitis. The Heart Protection Study revealed that there is no need for liver function monitoring in patients since there is no risk of hepatitis in...

  • Editorial: G-CSF Therapy for Severe Alcoholic Hepatitis: Targeting Liver Regeneration or Neutrophil Function? Moreau, MD, Richard; Rautou, MD, PhD, Pierre-Emmanuel // American Journal of Gastroenterology;Sep2014, Vol. 109 Issue 9, p1424 

    Abstract: Severe alcoholic hepatitis is a life-threatening liver disease. Although corticosteroid treatment is recommended and improves survival, mortality remains high and 35% of patients die within 6 months. There is no available medical treatment for patients who do not respond to...


Read the Article


Sign out of this library

Other Topics