TITLE

A multicentre longitudinal observational study of changes in self reported health status in people with Parkinson's disease left untreated at diagnosis

AUTHOR(S)
Grosset, D.; Taurah, L.; Burn, D. J.; MacMahon, D.; Forbes, A.; Turner, K.; Bowron, A.; Walker, R.; Findley, L.; Foster, O.; Patel, K.; Clough, C.; Castleton, B.; Smith, S.; Carey, G.; Murphy, T.; Hill, J.; Brechany, U.; McGee, P.; Reading, S.
PUB. DATE
May 2007
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;May2007, Vol. 78 Issue 5, p465
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: The issue of when to start treatment in Parkinson's disease (PD) remains controversial. Some favour treatment at diagnosis while others opt for a ‘wait and watch’ policy. The effect of the latter policy on the self reported health status of people with PD is unknown. Aims: To record self reported health status through longitudinal use of a validated PD specific questionnaire (PDQ-39) in untreated PD patients in multiple centres in the UK. To compare patients who were left untreated with those who were offered treatment during follow-up. Methods: A multicentre, prospective, real life observational audit based study addressing patient reported outcomes in relation to self reported health status and other sociodemographic details. Results: 198 untreated PD were assessed over a mean period of 18 months. During two follow-up assessments, the self reported health status scores in all eight domains of the PDQ-39 and the overall PDQ-39 summary index worsened significantly (p<0.01) in patients left untreated. In a comparative group in whom treatment was initiated at or soon after diagnosis, there was a trend towards improvement in self reported health status scores after treatment was started. Conclusions: This study addresses for the first time self reported health status, an indicator of health related quality of life, in untreated PD. The findings may strengthen the call for re-evaluation of the policy to delay treatment in newly diagnosed patients with PD.
ACCESSION #
25171617

 

Related Articles

  • Burn Specific Health Scale. McMahon, Margaret // Australian Journal of Physiotherapy;2008, Vol. 54 Issue 4, p284 

    The article focuses on the Burn Specific Health Scale (BSHS), a condition-specific health status instrument for use in people with burn injuries. It cites that the BSHS is a self-administered questionnaire. It notes that the BSHA-A contains 80 items across four domains, namely, physical, mental,...

  • Validation of a New Instrument for Self-care in Spanish Palliative Care Professionals Nationwide. Galiana, Laura; Oliver, Amparo; Sansó, Noemí; Benito, Enric // Spanish Journal of Psychology;2015 Supplement, Vol. 18, pN.PAG 

    Self-care is a cornerstone issue for those who deal with stressful events, as it is the case of palliative care professionals. It has been related to awareness, coping with death and quality of life, among others, but no measurement instruments have been used in palliative care professionals....

  • The Health Status Questionnaire: achieving concordance with published disability criteria. H.P. Jones // Archives of Disease in Childhood;Jan2002, Vol. 86 Issue 1, p15 

    Aim: To compare the Health Status Questionnaire with established methods of assessing disability in preterm and very low birthweight infants. Method: All survivors of gestational age <31 weeks or birth weight <1500 g, born in 1994 to women resident in Wales were identified. Assessments were by a...

  • Test Review: Patient Health Questionnaire—9 (PHQ-9).  // Rehabilitation Counseling Bulletin;Jul2014, Vol. 57 Issue 4, p246 

    The article offers information on the Patient Health Questionnaire-9 (PHQ-9), a diagnostic screening instrument to assess and monitor depression severity. Among topics discussed include items in the questionnaire, its practical application, and how relaibility of the questionnaire is assessed....

  • Your mouth’s dental state: A foreshadowing to your overall health.  // Dental Assistant;May/Jun2014, Vol. 83 Issue 3, p46 

    The article discusses how dental health can be an indicator to a persons overall health, the link between cardiovascular disease and the gum disease peri­odontitis and recommendations on dental care that can avoid diseases like periodontitis.

  • Assessment of Knowledge, Physical Health, Social Support and Self -Esteem among Persons with Haemophilia. Sulochana B.; Kurien, Annamma; Suvarna, Niveditha; George, Linu Sara // International Journal of Nursing Education;Jul-Dec2013, Vol. 5 Issue 2, p218 

    No abstract available.

  • Cross-diagnostic validity of the Nottingham health profile index of distress (NHPD). Wann-Hansson, Christine; Klevsgård, Rosemarie; Hagell, Peter // Health & Quality of Life Outcomes;2008, Vol. 6, Special section p1 

    Background: The Nottingham Health Profile index of Distress (NHPD) has been proposed as a generic undimensional 24-item measure of illness-related distress that is embedded in the Nottingham Health Profile (NHP). Data indicate that the NHPD may have psychometric advantages to the 6-dimensional...

  • The impact of nocturnal disturbances on daily quality of life in patients with Parkinson's disease. Rwei-Ling Yu; Chun-Hsiang Tan; Ruey-Meei Wu // Neuropsychiatric Disease & Treatment;Aug2015, Vol. 11, p2005 

    Objectives: The aims of this study were to explore nocturnal disturbances in patients with Parkinson's disease (PD) and to assess their impact on quality of life (QoL). Methods: A total of 211 patients with PD were recruited for this study, and each participant was evaluated using the...

  • Eradication of Helicobacter pylori Infection Improves Levodopa Action, Clinical Symptoms and Quality of Life in Patients with Parkinson's Disease. Hashim, Hasriza; Azmin, Shahrul; Razlan, Hamizah; Yahya, Nafisah Wan; Tan, Hui Jan; Manaf, M. Rizal Abdul; Ibrahim, Norlinah Mohamed // PLoS ONE;Nov2014, Vol. 9 Issue 11, p1 

    Background: Previous studies have demonstrated a higher prevalence of Helicobacter pylori (H. pylori) infection in patients with Parkinson's disease (PD) compared to controls. H. pylori infection affects levodopa absorption and its eradication significantly improves clinical response to...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics