Nonsteroidal antiinflammatory drugs did not increase risk for all-cause mortality in osteoarthritis

Lee, T. A.; Bartle, B.; Weiss, K. B.
May 2007
ACP Journal Club;May/Jun2007, Vol. 146 Issue 3, p77
Academic Journal
The article presents a study on the mortality, cardiovascular and cerebrovascular risks associated with the long-term nonsteroidal anti-inflammatory drug (NSAID) use in patients with osteoarthritis. Results revealed that exposure to any NSAID is associated with the decreased risk of death and the increased risks of cardiovascular and cerebrovascular diseases. It is concluded that NSAIDs are associated with an increased risk of cardiovascular or cerebrovascular disease.


Related Articles

  • Nonsteroidal antiinflammatory drugs did not increase risk for all-cause mortality in osteoarthritis: COMMENTARY. Gonzalez, Emilio B. // ACP Journal Club;May/Jun2007, Vol. 146 Issue 3, p77 

    The author comments on a study on the mortality, cardiovascular and cerebrovascular risks associated with the long-term nonsteroidal anti-inflammatory drug (NSAID) use in patients with osteoarthritis. He stated that the study used a nested case-control design and the issues with compliance in...

  • News in brief . . .  // Reactions Weekly;6/4/2005, Issue 1054, p4 

    Presents three medical research. Results of a study on the comparison of esomeprazole, lansoprazole and pantoprazole; Information on a study on nonsteroidal anti-inflammatory drug; Facts about a study on the cardiovascular risk factors after antenatal exposure to betamethasone.

  • Hip viscosupplementation under ultra-sound guidance riduces NSAID consumption in symptomatic hip osteoarthritis patients in a long follow-up. Data from italian registry. Migliore, A.; Granata, M.; Tormenta, S.; Laganà, B.; Piscitelli, P.; Bizzi, E.; Massafra, U.; Alimonti, A.; Maggi, C.; De Chiara, R.; Iannessi, F.; Sanfilippo, A.; Sotera, R.; Scapato, P.; Carducci, S.; Persod, P.; Denaro, S.; Camminiti, M.; Pagano, M. G.; Bagnato, G. // European Review for Medical & Pharmacological Sciences;2011, Vol. 15 Issue 1, p25 

    Introduction: Non-steroidal anti-inflammatory drugs (NSAIDs) consumption is strictly related to a high gastrointestinal and cardiovascular mortality and morbidity rate. Osteoarthritis Research Society International (OARSI) recommendations in patients with symptomatic hip or knee OA stated that...

  • Understanding NSAIDs, CV risks. Tanzi, Maria G. // Pharmacy Today;Sep2011, Vol. 17 Issue 9, p67 

    The article presents studies on the association between cardiovascular risks and the use of nonsteroidal anti-inflammatory agents (NSAIDs). The report, from a meta-analysis, proposes that cardiovascular risk is related with selective and nonselective NSAIDs. Other data revealed an increased risk...

  • Fine line between benefit and harm conferred by prophylactic aspirin.  // Reactions Weekly;6/4/2005, Issue 1054, p4 

    Discusses research being done on epidemiological modelling of routine use of low dose aspirin for the primary prevention of coronary heart disease and stroke in those aged greater than or equal to 70. Reference to a study by M. R. Nelson et al published in a 2005 online issue of the "British...

  • Aspirin resistance in patients with acute ischemic stroke. Ozben, Serkan; Ozben, Beste; Tanrikulu, Azra; Ozer, Feriha; Ozben, Tomris // Journal of Neurology;Nov2011, Vol. 258 Issue 11, p1979 

    Aspirin is used in ischemic stroke therapy. However, some patients are not responsive to the antithrombotic action of aspirin. The aim of this study was to assess the prevalence of aspirin resistance in stroke patients and its association with mortality. One-hundred and six patients (mean age...

  • Review: Nonselective nonsteroidal antiinflammatory drugs do not increase risk for cardiovascular events. Szmitko, Paul E.; Juurlink, David // ACP Journal Club;Jan/Feb2007, Vol. 146 Issue 1, p12 

    The article discusses a research study regarding the effect of nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) on cardiovascular events in patients with Alzheimer disease. Randomized placebo-controlled trials were conducted in which the effect of drugs such as naproxen, nabumetone,...

  • NSAID prescriptions unnecessary, unsafe for many older patients.  // Geriatrics;Jan98, Vol. 53 Issue 1, p22 

    Focuses on nonsteriodal anti-inflammatory drug (NSAID) prescriptions in relation to older patients with osteoarthritis. Details on the blinded study conducted by Allen Huang, and colleagues of the department of geriatrics at the Royal Victoria Hospital, Montreal; Findings of the study.

  • NSAIDs and Cardiovascular Risks... An Interview With Sharon Mulvagh, M.D.  // Mayo Clinic Women's Health Source;Nov2010, Vol. 14 Issue 11, p6 

    An interview with Sharon Mulvagh, a cardiologist at Mayo Clinic in Rochester, Minnesota, is presented. When asked about a study, which revealed that nonsteroidal anti-inflammatory drugs (NSAIDs) are associated with an increased risk of cardiovascular-related death in health adults, she responds...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics