Procalcitonin level-guided treatment reduced antibiotic use in exacerbations of COPD

Stolz, D.; Christ-Crain, M.; Bingisser, R.
May 2007
ACP Journal Club;May/Jun2007, Vol. 146 Issue 3, p57
Academic Journal
The article examines the antibiotic treatment of exabercations of obstructive pulmonary disease. At the index exabercation, procalcitonin guidance reduced antibiotic use more than did standard therapy and allowed sustained reduction in antibiotic exposure at up to six months. The secondary outcomes included improvement in symptoms, need for intensive care unit stay, length of hospital stay, mortality, exacerbation rate, and lung function.


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