Where are we going with preimplantation genetic diagnosis?
- ESHRE PGD Consortium data collection IV: Mayâ€“December 2001. K. Sermon; C. Moutou; J. Harper; J. Geraedts; P. Scriven; L. Wilton; M.C. Magli; A. Michiels; S. Viville; C. De Die // Human Reproduction;Jan2005, Vol. 20 Issue 1, p19
The ESHRE PGD Consortium was formed in 1997 to survey the practice of preimplantation genetic diagnosis (PGD). Since then, three reports have been published giving an overview on PGD from an ever-increasing number of centres and reporting on an increasing number of PGD cycles and pregnancies and...
- Should IVF centers offer preimplantation genetic diagnosis? No. PGD's technical difficulty, learning curve, and costs warrant caution. Sable, David B. // Contemporary OB/GYN;Mar2003, Vol. 48 Issue 3, p54
Stresses that fertilization in vitro (IVF) centers should not offer preimplantation genetic diagnosis (PGD). Potential of PGD as a diagnostic test; Limitations of the technology; Technical concerns on PGD.
- PGD gender selection for non-Mendelian disorders with unequal sex incidence. David J. Amor; Carolyn Cameron // Human Reproduction;Apr2008, Vol. 23 Issue 4, p729
Preimplantation genetic diagnosis (PGD) was originally developed for couples whose potential offspring were at risk of severe Mendelian disorders, but has since been extended to other indications. One possible use of PGD is to perform gender selection for couples whose offspring are at increased...
- Preimplantation genetic diagnosis for familial dysautonomia. Rechitsky, Svetlana; Verlinsky, O; Kuliev, A; Ozen, RS; Masciangelo, C; Lifchez, A; Verlinsky, Y // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Jun2003, Vol. 6 Issue 4, p488
Presents a study that investigated preimplantation genetic diagnosis for familial dysautonomia, resulting in a triplet pregnancy and birth of three unaffected children. Information on familial dysautonomia; Materials and methods used in the study; Results; Discussion.
- Current status of preimplantation diagnosis for single gene disorders. Verlinsky, Yury; Kuliev, Anver // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Sep2003, Vol. 7 Issue 2, p145
Preimplantation genetic diagnosis (PGD) has become an established procedure for avoiding the birth of affected children with single gene disorders. PGD is performed through polar body or blastomere biopsy, which has no deleterious effect on pre- and post-implantation development. This review...
- Preimplantation genetic diagnosis to prevent genetic disorders in children. Lashwood, Alison // British Journal of Nursing;1/27/2005, Vol. 14 Issue 2, p64
Preimplantation genetic diagnosis (PGD) is an alternative reproductive option for couples at risk of having a child affected with a genetic disorder. Although prenatal diagnosis (PND) has been available for many years, it is not acceptable to many owing to issues relating to termination of...
- Should IVF centers offer preimplantation genetic diagnosis? Yes. PGD can improve ART efficiency and practice standards. Kuliev, Anver; Verlinsky, Yury // Contemporary OB/GYN;Mar2003, Vol. 48 Issue 3, p54
Suggests that fertilization in vitro (IVF) centers should offer preimplantation genetic diagnosis (PGD). Advantages of using PGD; Overview of how PGD is used for chromosomal abnormalities; Clinical value in using PGD.
- Extending preimplantation genetic diagnosis: medical and non-medical uses. Robertson, J. A. // Journal of Medical Ethics;Aug2003, Vol. 29 Issue 4, p213
New uses of preimplantation genetic diagnosis (PGD) to screen embryos prior to transfer raise ethical, legal, and policy issues that deserve close attention. Extensions for medical purposes, such as to identify susceptibility genes, late onset disease, and human leukocyte antigen (HLA) matching,...
- Commentary: Preimplantation diagnosis raises a philosophical dilemma. Raeburn, J.A. // BMJ: British Medical Journal (International Edition);8/26/95, Vol. 311 Issue 7004, p540
Opinion. Focuses on the philosophical dilemma raised by preimplantation diagnosis. Ethics of selection of healthy embryos to implant; Derivation of singles cells by biopsy from pre-embryos formed in vitro as basis of preimplantation testing; Danger of discrimination carried by preimplantation...