TITLE

OCULAR TOXOPLASMOSIS : ATYPICAL PRESENTATION

AUTHOR(S)
J., Azlyn Azwa; W. M., Wan Norliza; M., Ibrahim
PUB. DATE
January 2006
SOURCE
Malaysian Journal of Medical Sciences;Jan2006 Supplement, Vol. 13, p176
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
INTRODUCTION: Toxoplasmosis is due to infestation by an obligatory intracellular protozoan parasite called Toxoplasma gondii. Ocular involvement in acquired toxoplasmosis is extremely rare. CASE REPORT: We report herein a case of atypical presentation of ocular toxoplasmosis in a young immunocompromised patient who was just diagnosed as retroviral positive. A 22-year old man who was an active intravenous drug user presented with sudden onset of painless reduced vision of both eyes for one day duration. He claimed that his visison was good previously. He also complained of severe frontal headache 1 week prior to the reduced vision. However there were no other symptoms of increased intracranial pressure. Ocular examinations showed significant reduced vision with presence of cotton wool spot in the posterior pole of both eyes. Radiological imaging showed evidenced suggestive of multiple cerebritis secondary to toxoplasmosis. Anti toxoplasma gondii was started immediately and patient respond well. CONCLUSION: Immunocompromised patient might present with an atypical ocular presentation and the diagnosis might be challenging.
ACCESSION #
25099232

 

Related Articles

  • Epidemiological and serological profiles of ocular toxoplasmosis in the municipality of Natal, northeastern Brazil. Mendes, Norma H. D.; Oliveira, Claudio B. S.; Garcia, Carlos A.; Holanda, Cecília M. X. C.; Andrade-Neto, Valter F. // Transactions of the Royal Society of Tropical Medicine & Hygiene;Oct2014, Vol. 108 Issue 10, p656 

    Background Toxoplasma gondii is the main culprit in most cases of infectious uveitis, in both acute and recurrent cases of congenital toxoplasmosis and acquired infections. Methods The ocular toxoplasmosis was evaluated in patients at the the reference unit in ophthalmology, in Rio Grande do...

  • A Brazilian report using serological and molecular diagnosis to monitoring acute ocular toxoplasmosis. Previato, Mariana; Batista Frederico, Fábio; Antunes Murata, Fernando Henrique; Camargo Siqueira, Rubens; Pires Barbosa, Amanda; Silveira-Carvalho, Aparecida Perpétuo; da Silva Meira, Cristina; Pereira-Chioccola, Vera Lúcia; Gava, Ricardo; Martins Neto, Plínio Pereira; de Mattos, Luiz Carlos; Brandão de Mattos, Cinara Cássia // BMC Research Notes;12/7/2015, Vol. 8, p1 

    Background: Toxoplasmosis was recently included as a neglected disease by the Center for Disease Control. Ocular toxoplasmosis is one clinical presentation of congenital or acquired infection. The laboratory diagnosis is being used worldwide to support the clinical diagnosis and imaging. The aim...

  • Unusual Abundance of Atypical Strains Associated with Human Ocular Toxoplasmosis. Grigg, Michael E.; Ganatra, Jyotsom; Boothroyd, John C.; Margolis, Tood P. // Journal of Infectious Diseases;9/1/2001, Vol. 184 Issue 5, p633 

    To facilitate genotyping of Toxoplasma gondii in vitreous fluid of patients with severe or atypical ocular toxoplasmosis, polymerase chain reaction (PCR) restriction fragment length polymorphism (RFLP) assays were developed for SAG3 (p43) and SAG4 (p18), 2 single-copy surface antigen genes....

  • Anti-retinal autoantibodies in experimental ocular and systemic toxoplasmosis. Garweg, Justus; Kozak, Yvonne; Goldenberg, Brigitte; Boehnke, Matthias // Graefe's Archive of Clinical & Experimental Ophthalmology;Apr2010, Vol. 248 Issue 4, p573 

    Patients with ocular toxoplasmosis (OT) develop autoreactivity to several retinal antigens, including retinal S-antigen. By establishing an experimental rabbit model of systemic and of primary and secondary ocular toxoplasmosis, we wished to investigate the onset and development of humoral...

  • Ocular toxoplasmosis common cause of ocular inflammation. Cunningham Jr., Emmett T. // Ophthalmology Times;10/1/2005, Vol. 30 Issue 19, p44 

    Presents comments from various experts on aspects related to toxoplasmic retinochoroiditis, a condition caused by Toxoplasma gondii infection. Toxoplasmic retinochoroiditis as the most prevalent form of posterior uveitis and the most frequent form of infectious uveitis in non-immunocompromised...

  • The Many Faces of Ocular Toxoplasmosis. Reynolds, Sherrol A.; Falco, Laura A.; Shechtman, Diana L.; Pizzimenti, Joseph J. // Review of Optometry;8/15/2012, Vol. 149 Issue 8, p67 

    The article presents several case studies on ocular toxoplasmosis caused by Toxoplasma gondii infection. A 41-year-old black male complaining of floaters in his left eye has been detected with retinitis and dilated retinal vein with superficial hemorrhages. An 18-year-old white male with...

  • Recently Acquired Toxoplasma gondii Infection, Brazil. Jones, Jeffrey L.; Muccioli, Cristina; Belfort Jr., Rubens; Holland, Gary N.; Roberts, Jacquelin M.; Silveira, Claudio // Emerging Infectious Diseases;Apr2006, Vol. 12 Issue 4, p582 

    The city of Erechim, Brazil, has a 17% prevalence of ocular toxoplasmosis, and type 1 Toxoplasma gondii predominates. To examine risk factors for acute T. gondii infection in this area, we administered a questionnaire to recently infected persons (n = 131) and seronegative controls (n = 110)....

  • Clinical Features and Treatment of Ocular Toxoplasmosis. Young-Hoon Park; Ho-Woo Nam // Korean Journal of Parasitology;Aug2013, Vol. 51 Issue 4, p393 

    Ocular toxoplasmosis is a disease caused by the infection with Toxoplasma gondii through congenital or acquired routes. Once the parasite reaches the retina, it proliferates within host cells followed by rupture of the host cells and invasion into neighboring cells to make primary lesions....

  • Toxoplasmosis Can Test Diagnostic Skills. Wertheim, Michael S.; Smith, Justine R.; Cunningham Jr., Emmett T.; Regillo, Carl // Review of Ophthalmology;Oct2004, Vol. 11 Issue 10, p140 

    The article reports that both the diagnosis and treatment options of Toxoplasmosis is a test for clinicians. Toxoplasmosis is an infection caused by the parasite toxoplasma gondii, which exists in three major forms: the oocyst, the tachyzoite or infectious form, and the tissue cyst or latent...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics