A multilayered take on gene expression

Flintoft, Louisa
June 2007
Nature Reviews Genetics;Jun2007, Vol. 8 Issue 6, p407
Academic Journal
The article reexamines a research paper entitled "A Network of Multiple Regulatory Layers Shapes Gene Expression in Fission Yeast," by D. H. Lackner and colleagues. In this study, the authors used genome-wide assays for levels of gene expression intermediates in Schizosaccharomyces pombe yeast cells under a set of standardized conditions. They also looked at the distribution of poly(A) tail lengths and messenger RNA half-lives to assess the effects of these features on gene expression.


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